Association Between Postoperative Cerebral Vascular Complication and Functional Prognosis and Cerebral Small Vascular Disease (CSVD) After Thoracic Surgery : an Exploratory Study
试验速览
- 阶段
- 不适用
- 入组人数
- 212
- 试验地点
- 1
- 主要终点
- Incidence of postoperative overt stroke
研究概览
简要总结
The investigators perform a retro-prospective exploratory cohort study among patients 65 to 85 years old with pre-operative head MRI result after thoracic surgery in Renji Hospital Affiliated to Shanghai Jiaotong University from November 2020 to December 2021. Perioperative data were collected, including preoperative general condition, laboratory examination, auxiliary examination (blood routine, blood coagulation, liver and kidney function, etc.), perioperative indicators （use of anesthetics, anesthetic time, blood pressure, etc.）, postoperative cerebral function follow-up and occurrence of cerebral vascular complications (brain infarction, brain bleed, etc.) of patients.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 65 Years 至 85 Years（Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •65≤age<85
- •after thoracic surgery
- •finish pre-operative brain MRI
排除标准
- •mental illness
- •existing dementia and other diseases: Alzheimer disease, dementia, Parkinson's disease, Huntington's disease, systemic lupus erythematosus, etc.
- •previous cerebral infarction or hemorrhage
结局指标
主要结局
Incidence of postoperative overt stroke
时间窗: 1 year after surgery
Postoperative overt stroke detected by MRI of the brain
次要结局
- Physical function after surgery as assessed using Activities of Daily Living (iADL) Scale(1 year after surgery)
- Physical function after surgery as assessed using the Modified Rankin Scale(1 year after surgery)