Head in the Game - a study on long-term effects of playing elite football on brain structure and functio
- Conditions
- brain damage10029305
- Registration Number
- NL-OMON46652
- Lead Sponsor
- Fédération Internationale de Fotoball Association (FIFA)
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- Not specified
- Target Recruitment
- 80
two groups of atheltes will be included in this study:;50 football players
- female, aged 30-50 years
- played at least 5 mathces in a first league club team or the national team
- retired from elite football over 2 years ago (no first league or international matches);30 elite athletes from non-contact sports
- age, gender and handedness matched
- former elite athlete (over 5 competitions at national or international level) in a non-contact sport or anthoer sport with a low risk of head injury
- Retired from elite sports over 2 years ago (no competition on national or international level)
Football players
* Previous non-football-related severe head injury diagnosed or treated by a physician
* Symptomatic mental disorder (e.g. depression or schizophrenia).
* Symptomatic chronic disease (i.e. cancer, diabetes, cardiovascular disease) except osteoarthrosis/-arthritis and medically controlled hypertension.
* MRI contra-indications (specified below).;Elite athletes
* Previous or current regular participation (* once a week for *1 year) in football, or other sports with high risk of head injury.
* Previous severe head injury diagnosed or treated by a physician.
* Symptomatic mental disorder (e.g. depression, schizophrenia).
* Symptomatic chronic disease (i.e. cancer, diabetes, cardiovascular disease, dementia), except osteoarthrosis/-arthritis and medically controlled hypertension.
* MRI contra-indications (specified below).;MRI Contraindication
* Pregnancy (even though there is no evidence of adverse effects).
* Metal and/or recently implanted joint replacements.
* Implanted electric and electronic devices are a strict contraindication to magnetic resonance imaging, and in particular: heart pacemakers (especially older types), insulin pumps, implanted hearing aids, neuro-stimulators, intracranial metal clips, metallic bodies in the eye.
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>* Neurocognitive performance including the following domains: sustained, simple<br /><br>and complex attention, verbal and visual memory, executive function, verbal<br /><br>fluency, visuospatial skills, psychomotor speed, reaction time, reasoning,<br /><br>motor speed, working memory, processing speed and cognitive flexibility<br /><br>* Functional/structural connectivity within the DMN and SN</p><br>
- Secondary Outcome Measures
Name Time Method <p>* Previous head injuries<br /><br>* Mental and neurologic health, e.g. Depression, ADHD, Anxiety, Migraine<br /><br>* QOL<br /><br>* Personal and sports career related variables, e.g. age, heading frequency,<br /><br>career length, playing position</p><br>