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Clinical Trials/NCT01405664
NCT01405664
Completed
N/A

A Randomized, Controlled Clinical Trial to Evaluate the Effect on Patient Outcomes of Weight Bearing Status After Forage of Osteochondral Defects of the Ankle

Nova Scotia Health Authority1 site in 1 country68 target enrollmentSeptember 1, 2011

Overview

Phase
N/A
Intervention
Not specified
Conditions
Osteochondritis Dissecans of Ankle and Joints of Foot
Sponsor
Nova Scotia Health Authority
Enrollment
68
Locations
1
Primary Endpoint
Ankle Osteoarthritis Scale
Status
Completed
Last Updated
last year

Overview

Brief Summary

The rationale for this research study is to evaluate the effect on clinical outcomes of weight bearing as tolerated after forage surgery for the treatment of osteochondral defects of the ankle, thus potentially eliminating the need for a period of immobilisation or non-weight bearing after surgery.

The investigators hypothesize that their will be no difference in functional outcomes between weight bearing as tolerated as compared to non-weight bearing for six weeks after forage surgery for OCD of the ankle.

Detailed Description

The hypothesis for advantage of the investigational post-operative therapy is based on: Equivalent clinical outcomes to non-weight bearing; Similar radiographic findings on CT at follow-up visit between the two groups; reduced morbidity and disability to subjects through elimination of a period of non-weight bearing; reduction of cost to patients by eliminating need for adjuvant walking and mobility aids (crutches, taxis) and time off work.

Registry
clinicaltrials.gov
Start Date
September 1, 2011
End Date
September 30, 2023
Last Updated
last year
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Patients aged 16-60 years
  • No prior ankle surgery
  • Able and willing to comply with follow-up
  • Capable of provide informed consent
  • Medically fit for surgery
  • Lesions on preoperative CT Scan \< 1.5cm
  • Symptomatic (ie:pain, restricted activities, inability to WB, decreased ROM)
  • Single Isolated lesion
  • Failure of conservative treatment (3 months of limited activities and/or weight bearing and/or immobilization)

Exclusion Criteria

  • Age less than 16 years or greater than 60 years
  • Inflammatory arthritis
  • Diffuse osteoarthritis of affected joint
  • Associated fracture
  • Prior ankle surgery for current injury (including arthroscopy)
  • Unable to comply with follow-up
  • Unable to provide informed consent
  • Bernt \& Hardy class IV (amenable to ORIF)
  • Multiple osteochondral defects in one ankle or touching osteochondral lesions of tibia and talus
  • Prior osteochondral defects of the affected ankle

Outcomes

Primary Outcomes

Ankle Osteoarthritis Scale

Time Frame: 12 months

Pain and disability outcomes assessed on scale of 1-100. The higher the score is more pain\\disability

Secondary Outcomes

  • CAT Scan(12months)

Study Sites (1)

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