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Clinical Trials/NCT05073276
NCT05073276
Recruiting
N/A

Non-Weight Bearing Versus Partial Controlled Weightbearing During the First Six Weeks of Rehabilitation After Multiple Knee Ligament Reconstruction: a Randomized Controlled Trial

Twin Cities Orthopedics1 site in 1 country50 target enrollmentJanuary 1, 2020
ConditionsKnee Injuries

Overview

Phase
N/A
Intervention
Not specified
Conditions
Knee Injuries
Sponsor
Twin Cities Orthopedics
Enrollment
50
Locations
1
Primary Endpoint
Gapping (mm) measured on Standard of Care Varus stress radiographs
Status
Recruiting
Last Updated
last year

Overview

Brief Summary

This is a prospective randomized controlled trial with the purpose to determine if patients undergoing isolated posterior cruciate ligament (PCL) reconstruction, or isolated medial collateral ligament (MCL) reconstruction, or combined PCL, anterior cruciate ligament (ACL), fibular collateral ligament (FCL), posterolateral corner (PLC), and MCL reconstructions (or any combination of multiple ligaments) can safely begin partial controlled weightbearing for the first six weeks after surgery.

Detailed Description

Patients will be randomly assigned to one of two rehabilitation protocols for the first six weeks post-surgery: 1. non-weightbearing 2. partial weightbearing An immobilizer brace in extension will be used from post-operative day 0 through 4 and a dynamic stabilizing posterior knee brace (Ossur) will be used from 5 days through 6 months post-surgery to protect against increased posterior translation forces due to gravity and while weightbearing for patients with PCL reconstructions. Specific Aims 1. Primary Aim: To determine if there is clinical equivalence in millimeters of posterior tibial translation on posterior stress radiographs at six months post-surgery between patients who are non-weightbearing versus partial controlled weightbearing during the first six weeks of post-surgical rehabilitation. 2. Primary Aim: To determine if there is clinical equivalence in millimeters of valgus and/or varus compartment gapping on stress radiographs at six months post-surgery between patients who are non-weightbearing versus partial controlled weightbearing during the first six weeks of post-surgical rehabilitation. 3. Secondary Aim: To determine if there is a difference in pain, edema, range of motion, gait, and quadriceps strength between groups. The current standard of care for posterior cruciate ligament reconstruction and multiligament reconstruction is non-weightbearing for the first six weeks after surgery.

Registry
clinicaltrials.gov
Start Date
January 1, 2020
End Date
January 2026
Last Updated
last year
Study Type
Interventional
Study Design
Single Group
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • ≥ 14 years old, \<60
  • Reconstruction of PCL alone
  • Reconstruction of MCL alone
  • Reconstruction of combined multiligament injuries (PCL+ (FCL, PLC, ACL, MCL))
  • Reconstruction of multiligament injuries (ACL+MCL)
  • Males or females
  • Is willing and able to comply with the clinical trial plan and able to understand and sign the Patient Informed Consent Form.

Exclusion Criteria

  • \< 14 years old
  • \>60 years old
  • Revision PCL reconstructions
  • Previous or concurrent vascular injury (vascular bypass procedure)
  • Associated fractures requiring concurrent surgery
  • Concurrent meniscal root or radial repair surgery

Outcomes

Primary Outcomes

Gapping (mm) measured on Standard of Care Varus stress radiographs

Time Frame: 6 months post-surgery

stress radiographs

Secondary Outcomes

  • Measurements by physical therapists (range of motion)(4,7, and 10 months after surgery)
  • Numeric Pain Scale (NPS) (0-10 rating)(Baseline and 6 months)
  • Measurements by physical therapists (Edema, thigh circumference)(4,7, and 10 months after surgery)
  • Measurements by physical therapists (Quadriceps strength, gait analysis)(4,7, and 10 months after surgery)
  • Patient reported outcome scores(Baseline, 3 months, 6 months, 1 year)

Study Sites (1)

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