Changes in body functions before and after intravenous caffeine in neonates with birth related brain injury
Not Applicable
- Conditions
- Health Condition 1: G968- Other specified disorders of central nervous system
- Registration Number
- CTRI/2024/04/065198
- Lead Sponsor
- Reema Garegrat
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
All male and female newborns with hypoxic ischemic encephalopathy till 30 days of life
Exclusion Criteria
No sex is excluded.
Age beyond 30 days is excluded
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Change in cerebral oxygenation pre and post caffeine administrationTimepoint: Change in cerebral oxygenation pre and post caffeine administration between 36 to 50 hours of life only. <br/ ><br>Baseline 2 hours before administering caffeine and second 2 hours after administering caffeine
- Secondary Outcome Measures
Name Time Method Change in renal and Splanchnic oxygenation index pre and post caffeine administration <br/ ><br>Change in Cerebral, mesenteric, celiac artery doppler pre and post caffeine administration <br/ ><br>Seizure burden before and after caffeine <br/ ><br>Heart Rate Variability index before and after caffeine <br/ ><br>NPASS (Pain score) before and after caffeine <br/ ><br>Timepoint: Before and after caffeine administration between 36 to 50 hours of age