NCT05550454
Completed
Not Applicable
Comparison of Manual Ventilation and Automatic Mechanical Ventilation During Cardiopulmonary Resuscitation, Pilot & Feasibility Study
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Out-Of-Hospital Cardiac Arrest
- Sponsor
- Seoul National University Hospital
- Enrollment
- 60
- Locations
- 1
- Primary Endpoint
- ROSC: return of spontaneous circulation
- Status
- Completed
- Last Updated
- 3 years ago
Overview
Brief Summary
Comparison of Manual Ventilation and Automatic Mechanical Ventilation during CPR, Pilot & Feasibility Study (CAVE-I trial)
Detailed Description
This is a preliminary randomized clinical trials comparing the effectiveness of the automatic mechanical ventilation method compared to manual ventilation methods commonly performed during advanced cardiac life support (ACLS) in emergency room for out-of-hospital cardiac arrest.
Investigators
Jong Hwan Shin
Associate Professor
Seoul National University Hospital
Eligibility Criteria
Inclusion Criteria
- •Out-of-hospital cardiac arrest (OHCA)
- •Transferred by only EMS without prehospital return of spontaneous circulation (ROSC)
- •ACLS for at least 20 minutes in the emergency room
- •Arterial blood gas analysis at least once during ACLS
Exclusion Criteria
- •In-hospital cardiac arrest (IHCA)
- •Not transferred by Emergency Medical Service
- •ROSC gained before arriving at the ER
- •OHCA caused by trauma
- •ACLS is not performed for more than 20 minutes because the death is obvious
- •Not able to intubate the trachea
Outcomes
Primary Outcomes
ROSC: return of spontaneous circulation
Time Frame: Within 20 minutes of ACLS
Rate of any ROSC after ACLS
Secondary Outcomes
- Arterial blood gas analysis (ABGA) parameters(The first test was conducted within 5 minutes of ACLS, and the second test 10 minutes after the first test.)
- Ventilation parameters(During the entire ACLS time after randomization and endotracheal intubation)
Study Sites (1)
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