Soutien Des Soins Informels Aux Personnes âgées Fragiles : Accompagnement Des Aidants Sur Base d'Une évaluation Clinique et Biologique de la Charge de Soins.
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Caregivers
- Sponsor
- Centre Hospitalier Universitaire UCLouvain Namur
- Enrollment
- 150
- Locations
- 1
- Primary Endpoint
- Levels of biomarkers across groups
- Last Updated
- 10 years ago
Overview
Brief Summary
Providing care for a disabled elderly may represent a risk for the health of the caregiver. The objective of the study is to assess the impact of caregiving in terms of clinical and biological markers in relation to disability and cognitive impairment.
Detailed Description
The investigators hypothesize that an accumulation of stressful events related to care giving may induce a stress response to the caregiver. This stress response can be measured by biological markers (inflammation, transcription and immunity) and also by clinical markers (frailty, physical performance, nutrition). This stress response can be influenced by the subjective burden of the caregiver and by the severity of the disease of the care receiver (Activity of daily life capabilities, cognitive function, behavioral disturbance).
Investigators
Professor Maximilien Gourdin
Directeur Médical adjoint aux missions universitaires
Centre Hospitalier Universitaire UCLouvain Namur
Eligibility Criteria
Inclusion Criteria
- •living with the care-receiver ( or with a healthy elderly for the controls)
- •care-receiver dependent for at least one Activity of the daily living ( Katz index) or having cognitive disorder ( \>2 Global Deterioration Scale)
Exclusion Criteria
- •institutionalised elderly
- •inability to understand and speak french
- •Acute disease within the past month
- •Anti-inflammatory or immuno-suppressive treatment
- •End-of-life care
Outcomes
Primary Outcomes
Levels of biomarkers across groups
Time Frame: at baseline
biomarkers of inflammation (cortisol, high sensitive C-Reactive Protein,Interleukin-6), immunity (TRECS, telomere length) and transcriptomics/epigenetics
Secondary Outcomes
- Relation between biomarkers, subjective burden and the care receiver situation(at baseline)