Comparative evaluation of the clinical outcomes of xenogeneic pericardial collagen membrane enriched with two different forms of platelet concentrates in the treatment of gingival recession- A prospective study
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 发起方
- 入组人数
- 46
- 试验地点
- 1
- 主要终点
- To assess and compare the changes in the recession height from baseline to 6 months, within and between the study groups
研究概览
简要总结
Gingival recession is a common periodontal condition where the apical migration of gingival tissue causes exposure of the root surface and results in hypersensitivity, root caries , esthetic concerns to patients. The coronally advanced flap (CAF) along with connective tissue graft (CTG) is one of the most effective techniques for the management of Miller Class I and II recessions because it offers excellent esthetic results, highest root coverage. However, in patients with multiple gingival recession defects and having thin gingival phenotype, harvesting CTGs of adequate dimensions are clinically challenging due to the limited donor area. Recently the animal derived xenogeneic collagen membrane along with platelet concentrates have gained attention in successful root coverage procedures . In this study we are proposing to compare the efficacies of xenogeneic collagen membrane along with two different types of platelet concentrates, that is, injectable platelet rich fibrin versus advanced platelet rich fibrin plus
研究设计
- 研究类型
- Interventional
- 分配方式
- Coin toss, Lottery, toss of dice, shuffling cards etc
- 盲法
- Participant and Outcome Assessor Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 65.00 Year(s)（—）
- 性别
- All
入选标准
- •Systemically healthy subjects with an age range of 18-65 years.
- •Individuals diagnosed with recession defects in maxillary anteriors and premolars (Cairo’s RT1 , RT2 classes of recession)
- •Sites with minimum depth of recession ≥2mm.
- •Isolated or multiple adjoining recession involving ≤3 teeth.
排除标准
- •Sites with probing pocket depth ≥4mm.
- •2.Teeth with mobility and/or associated with trauma from occlusion.
- •Sites with dental caries and prosthetic restorations.
- •Patients who exhibit unacceptable oral hygiene compliance during/or after phase Ι therapy.
- •Pregnant and lactating women.
- •7.Patient known allergic response with equine derived substances.
- •8.Patients with known platelet disorders or using any medication that are known to interfere with platelet function.
- •Patients with systemic conditions or disease influencing the course of periodontal disease and therapy.
结局指标
主要结局
To assess and compare the changes in the recession height from baseline to 6 months, within and between the study groups
时间窗: Baseline and 6months
次要结局
- 1. To assess and compare the percentage of complete root coverage (CRC%) achieved at 6 months between the research groups(2.To assess and compare the patient perception regarding esthetics following the treatment modalities by using Visual Analogue Scale scores (VAS-E))
研究者
Kiran choudhary
SRM dental college