A randomised trial to assess the efficacy of arthemeter lumifantrine and dihydroartemisinin-piperquine in the treatment of uncomplicated malaria and its effects on transmission in Kenya

Completed

• Conditions: Malaria, Plasmodium falciparum infection; Infections and Infestations; Malaria

• Registration Number: ISRCTN36463274
• Lead Sponsor: Royal Tropical Institute (KIT) (The Netherlands)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2007-02-01
• Last Update Posted: 13 January 2015

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 150

Inclusion Criteria

1. Age six months to 12 years
2. Resident in research area and able to complete follow up
3. Temperature higher than 37.5°C but lower than 39.5°C or history of fever in last 24 hours
4. Understanding the procedures of the study by parents or guardian (informed consent)
5. Diagnosed with uncomplicated malaria (P. falciparum) only
6. Parasitaemia 100 - 100.000 parasites/ul

Exclusion Criteria

1. General danger signs, severe malaria or severe anaemia
2. Severe malnutrition
3. Presence of diseases other than malaria causing febrile conditions
4. Unwilling to participate and sign informed consent form

Study & Design

• Study Type: Interventional
• Study Design: Not specified