Thoracic Epidural Versus General Anesthesia for Laparoscopic Cholecystectomy

Not Applicable

Completed

• Conditions: General Anesthesia; Epidural Anesthesia
• Interventions: Drug: general anesthesia effect on heart rate in Laparoscopic Cholecystectomy; Drug: Thoracic epidural effect on heart rate in Laparoscopic Cholecystectomy (bupivacaine and lignocaine)

• Registration Number: NCT04721054
• Lead Sponsor: Armed Forces Hospital, Pakistan

Brief Summary

Eighty two patients planned to undergo elective laparoscopic cholecystectomy were divided into two groups, T and G, randomly. In Group T all patients underwent laparoscopic cholecystectomy under thoracic epidural anesthesia with 12mlof 0.25% bupivacaine and 1% lignocaine plain whereas in group G all patients underwent surgery under general anesthesia. Intra-operative heart rate, mean arterial pressure (MAP) and post operative opioid consumption in first 24hrs were recorded as primary outcomes whereas presence or absence of respiratory complication and duration of hospital stay as secondary outcome.

Detailed Description

Not available

Study Timeline

• Study Start: 2018-10-01
• Primary Completion: 2019-10-31
• Study Completion: 2019-10-31
• Status Verified: 2021-01
• Study First Submitted: 2021-01-02
• Study First Submitted QC: 2021-01-21
• Last Update Submitted: 2021-01-21
• Study First Posted: 2021-01-22
• Last Update Posted: 2021-01-22

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 82

Inclusion Criteria

1. patients having ASA statusI-III
2. age more than 18 years,
3. both genders
4. planned to undergo laparoscopic cholecystectomy

Exclusion Criteria

1. Patients who did not give consent,
2. Allergic to local anesthetic
3. Hemodynamically unstable,
4. Pregnant, full stomach patients

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
group receiving thoracic general anesthesia	general anesthesia effect on heart rate in Laparoscopic Cholecystectomy	-
group receiving thoracic epidural anesthesia	Thoracic epidural effect on heart rate in Laparoscopic Cholecystectomy (bupivacaine and lignocaine)	-

Primary Outcome Measures

Name	Time	Method
effectiveness of thoracic epidural anesthesia with general anesthesia for Laparoscopic cholecystectomy in terms of change in heart rate during surgery in immediate 24 hours-heart rate.	changes in heart rate at 24 hours of surgery.	the efficacy of thoracic epidural anesthesia was compared with general anesthesia for laproscopic cholecystectomy in the immediate post operative period in terms of intra operative heart rate.
effectiveness of thoracic epidural anesthesia with general anesthesia for Laparoscopic cholecystectomy in terms of change in mean arterial blood pressure during surgery in immediate 24 hours-mean arterial blood pressure.	changes in mean arterial pressure at 24 hours of surgery	efficacy of thoracic epidural anesthesia was compared with general anesthesia for laproscopic cholecystectomy in the immediate post operative period in terms of mean arterial blood pressure intra operatively and in immediate post operative period

Trial Locations

Locations (1)

Military Hospital; 🇵🇰 Rawalpindi, Punjab, Pakistan