Best Cutoff Value of Lactate Concentration in Vaginal Fluid to Predict Time of Spontaneous Onset of Labor in PPROM
- Conditions
- Aim is to Investigate Association Between Lactate Concentration in Vaginal Fluid and Time of Spontaneous Onset of Labor in PPROM
- Registration Number
- NCT03463811
- Lead Sponsor
- Mennatallah Mohamed Elnemr
- Brief Summary
The present study is aimed to assess whether lactate determination in vaginal fluid is associated with and can predict onset of labor for women with suspected preterm prelabor rupture of membranes (PPROMs).
- Detailed Description
Study design: Prospective observational cohort
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- Female
- Target Recruitment
- 42
Inclusion Criteria
- Age 25-35 years old
- BMI 25-30
- Singleton pregnancy in presentation with a history of suspected PPROM
- A live fetus with gestational age between 26+0 weeks and 34+0 weeks
Exclusion Criteria
- Abruption placenta
- Medical disorders and hypertensive disorders of pregnancy
- Intrauterine fetal death
- Known or suspected fetal anomalies
- Signs of infection (Fever, increase total leucocytic count)
- Multiple pregnancy.
- Regular uterine contractions.
- History of cervical insufficiency
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Time from examination to spontaneous onset of labor 48 hours Time from examination to spontaneous onset of labor \< or \> 48 hours according to concentration of lactate in vaginal fluid
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Ain shams
🇪🇬Cairo, Egypt