Randomized Controlled Trial of Duration of Antibiotic Prophylaxis in Head and Neck Surgery with Free Flap Reconstruction, HEDAX Trial

Phase 4

• Conditions: Head & Neck Cancer; Post-operative Infection; Cancer - Head and neck; Surgery - Surgical techniques; Infection - Other infectious diseases

• Registration Number: ACTRN12624000370505
• Lead Sponsor: The Royal Melbourne Hospital, Melbourne Health

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2024-03-28
• Last Update Posted: 15 April 2024

Recruitment & Eligibility

• Status: ot yet recruiting
• Sex: All
• Target Recruitment: 526

Inclusion Criteria

• Aged greater than or equal to 18 years of age
• Undergoing tumour resection and primary free flap reconstructive surgery for upper aerodigestive tract defects
• Clean-contaminated procedure (Centers for Disease Control and Prevention [CDC] criteria)

Exclusion Criteria

Patients who are unable to consent for themselves (e.g., due to cognitive or intellectual impairment)

Study & Design

• Study Type: Interventional
• Study Design: Not specified