Mental Practice and Manipulative Skills Training in Multiple Sclerosis

Not Applicable

Completed

• Conditions: Multiple Sclerosis
• Interventions: Other: Mental practice; Other: Mental practice + skill training; Other: Control group

• Registration Number: NCT04325074
• Lead Sponsor: Cristina García-Bravo

Brief Summary

Introduction: Multiple sclerosis (MS) is a demyelinating disease of the central nervous system which produces both motor and cognitive dysfunctions. MS causes a decline in the performance of activities of daily living (ADL) due to impairments affecting limb function.

Aim: This pilot study sought to determine whether the use of mental practice (MP) or the combined use of MP and the training of manipulative skills would improve the manipulation motor skills and treatment satisfaction among people with MS.

Methods: The study participants were people with MS. Blinded evaluators performed three assessments for each patient (pre-treatment, post-treatment and at a three month follow up). The patients were divided into three groups with alternate allocation: (A) Mental practice, (B) Mental practice + skills training and (C) Control group.

Keywords: activities of daily living; manual dexterity; mental practice, motor image; multiple sclerosis.

Detailed Description

Not available

Study Timeline

• Study Start: 2015-09-15
• Primary Completion: 2015-11
• Study Completion: 2016-06
• Status Verified: 2020-03
• Study First Submitted: 2020-03-18
• Study First Submitted QC: 2020-03-25
• Last Update Submitted: 2020-03-25
• Study First Posted: 2020-03-27
• Last Update Posted: 2020-03-27

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

• patients diagnosed with MS of the RRMS and SPMS subtypes, without the presence of flare-ups during the past three months and aged between 25 and 60 years;
• an Expanded Disability Status Scale (EDSS) score of ≤7,
• not presenting depressive symptoms (measured using the Beck Depression Inventory, BDI),
• not presenting cognitive decline, measured using the Montreal Cognitive Assessment (MoCA) or Minimental Status Examination.
• In addition, they had to be regularly attending physical therapy and/or occupational therapy rehabilitation treatments.

Exclusion Criteria

Not provided

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Mental practice	Mental practice	The final sample therefore comprised of 35 participants (n=35), who were divided into three treatment groups. The sample of mental practice group was n=12.
Mental practice + skill training	Mental practice + skill training	The final sample therefore comprised of 35 participants (n=35), who were divided into three treatment groups. The sample of mental practice + skills training group was n=13.
Control group	Control group	The final sample therefore comprised of 35 participants (n=35), who were divided into three treatment groups. The sample of control group was n=10.

Primary Outcome Measures

Name	Time	Method
The Canadian Occupational Performance Measure (COPM). Pre-treatment	Pre-treatment assessments were performed with each patient.	The higher scores mean a better outcome.
Nine Hole Peg Test (NHPT). Pre-treatment	Pre-treatment assessments were performed with each patient.	The higher scores mean a worse outcome.
Box and Block Test (BBT). Pre-treatment	Pre-treatment assessments were performed with each patient.	The higher scores mean a better outcome.
The ABILHAND questionnaire. Pre-treatment	Pre-treatment assessments were performed with each patient.	The higher scores mean a better outcome.

Secondary Outcome Measures

Name	Time	Method
Nine Hole Peg Test (NHPT). Post-treatment	Immediately after treatment assessments were performed with each patient.	The higher scores mean a worse outcome.
Box and Block Test (BBT). Post-treatment	Immediately after treatment assessments were performed with each patient.	The higher scores mean a better outcome.
The Canadian Occupational Performance Measure (COPM). Post-treatment	Immediately after treatment assessments were performed with each patient.	The higher scores mean a better outcome.
The ABILHAND questionnaire. Post-treatment	Immediately after treatment assessments were performed with each patient.	The higher scores mean a better outcome.