Group work for children with Tourette Syndrome (TS)

Not Applicable

Completed

• Conditions: Topic: Generic Health Relevance and Cross Cutting Themes; Subtopic: Generic Health Relevance (all Subtopics); Disease: Paediatrics; Mental and Behavioural Disorders

• Registration Number: ISRCTN50798741
• Lead Sponsor: Great Ormond Street Hospital For Children NHS Foundation Trust (UK)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2014-01-16
• Last Update Posted: 28 November 2016

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 48

Inclusion Criteria

Participants will be recruited from the specialist TS Clinic at Great Ormond Street Hospital. All children seen at the clinic over the past five years will be invited retrospectively. New referrals to the clinic during recruitment will also be considered.
Inclusion criteria will be:
1. Male or female children aged 9-14yrs
2. Diagnosis of Tourette Syndrome or Chronic Tic Disorder
3. Score on YGTSS (Yale Global Tic Severity Scale) > 13
4. Ideally live within one hour of London

Exclusion Criteria

1. Learning Disability [Full Scale Intelligence Quotient (FSIQ) < 80, following Piacentini et al., 2010 and Woods et al., 2011]
2. Psychotic symptoms
3. Those who have had more than four sessions of HRT or Comprehensive Behavioral Intervention for Tics (CBIT) before (as in Piacentini et al., 2010 and Woods et al., 2011)
4. Those who have attended a psycho-educational group within the last two years
5. Children who do not speak English as a first language
6. Current substance abuse / dependence
7. Those who do not have internet access at home (a requirement for the tests used during home visits)

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Tic severity, which will be measured using the Yale Global Tic Severity Scale (Leckman et al., 1989), is a well validated semi-structured clinical interview carried out with parent and child. Questions relate to tic severity over the previous week. Separate ratings are recorded for motor and phonic tics in terms of number, frequency, intensity, complexity, and interference. These are combined to give an overall tic severity score.<br>Measures to characterise the groups<br>1. Parent and child versions of the 32-item ChOCI-R self-report scale (Uher et al., 2008) as a measure OCD symtomatology.<br>2. A seven subtest short-form version of the Wechsler Intelligence Scales for Children (Crawford et al., 2010) as a measure of intellectual ability.