To study the influence of Vitamin D3 supplements on the available bone quality and success of dental implants in mandibular posterior region in Indian population. -In Vivo Study
试验速览
- 阶段
- 3 期
- 状态
- 已完成
- 发起方
- 入组人数
- 33
- 试验地点
- 1
- 主要终点
- Influence of Vitamin D3 supplements on available bone quality and success of dental implants in mandibular posterior region
研究概览
简要总结
Long-term stable dental implants are the primary goal in the field of oral implantology. In order to achieve long-term success, the primary requisite is the phenomenon of osseointegration which is defined as a direct connection established between the bone and the implant surface, without the interposition of fibrous tissue. A low level of vitamin D has been associated with increased risk of implant failure. Recognition of various systemic risk factors associated with dental implants has shown that failure rates can be reduced, and predictability of success can be increased with introduction of Vitamin D3 supplements.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- None
入排标准
- 年龄范围
- 18.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- All
入选标准
- •Patients having at least one edentulous site for implant placement in mandibular posterior region.
- •Patients having minimum available tentative interocclusal space of 6-7 mm at the restorative site.
- •Patients with good oral hygiene.
- •Patients in the age group of 18 to 60 years.
- •Systemically healthy patients.
排除标准
- •Patients with extremely low vitamin D less than 10 ng per dl.
- •Insufficient inter arch space.
- •Insufficient width and height requiring complex surgical procedures such as grafting or ridge split.
- •Unfavourable implant axis orientation.
- •Patients with TMJ disorders.
- •Immunocompromised patients.
- •Blood dyscrasias.
- •Heavy smokers more than 10 cigarettes per day.
- •Alcohol abusers.
- •Occlusal anomalies.
- •Parafunctional habits.
- •Recent history of acute illness.
- •Organic heart disease with marked signs of cardiac insufficiency.
- •Recent myocardial infarction of less than 6 months duration.
- •Unstable angina.
- •Patients with advanced degrees of pulmonary, renal or endocrine insufficiency.
- •Uncontrolled diabetes with complications to vascular or other organs.
结局指标
主要结局
Influence of Vitamin D3 supplements on available bone quality and success of dental implants in mandibular posterior region
时间窗: 3 MONTHS
次要结局
- Evaluate and compare role of Vitamin D3 on crestal bone loss and implant stability at time of loading and 3 months post loading(1 year 6 months)
研究者
Dr. Udita Choudhry
SGT UNIVERSITY