Assessment of the Locally Administrated Vitamin D3 and Corticision Efficacy on Orthodontic Canine Retraction: A Prospective Clinical Study
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 16
- 试验地点
- 1
- 主要终点
- Rate of canine retraction
研究概览
简要总结
To study the effect vitamin D effect on orthodontic tooth movement when used in combination with coticision technique, independent t test or an equivalent non-parametric test will be used for comparison. According to a previous study by (S. T. Varughese, et al. (2019) , "Effect of vitamin D on canine distalization and alveolar bone density using multi-slice spiral CT: a randomized controlled trial
详细描述
Assessment of the locally administrated vitamin D3 and corticision efficacy on orthodontic canine retraction: A prospective clinical study
Protocol submitted in partial fulfillment of the requirements for the Master Degree in dental science in Orthodontics By Mahmoud Elsaid Elsayed Ahmed BDS 2017, Faculty of Dental Medicine, Boys, Cairo Al-Azhar University Dentist at armed forces hospitals Supervisors
Department of Orthodontics Faculty of Dental Medicine (Boys-Cairo) Al-Azhar University 2024G - 1446H
- Introduction Accelerating the rate of tooth movement is desirable to patients because it shortens treatment time and also to orthodontists because treatment duration has been linked to an increased risk of gingival inflammation, decalcification, dental caries, and root resorption.
The average duration of comprehensive orthodontic treatment is less than 2 years with a mean of 19.9 months. But sometimes, prolonged periods of wearing oral braces, particularly non cosmetic appliances, tend to keep patients, especially adults, away from seeking treatment, even when it is clearly indicated. Moreover, longer treatment durations are expensive for both the patient and the orthodontist. Therefore, one of the best ways to overcome this problem is to speed up the velocity of tooth movement from its usual rate of 0.8-1.2 mm/month (when continuous forces are applied).
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 13 Years 至 20 Years（Child, Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Orthodontic patients referred for therapeutic extraction of bilateral maxillary first premolars (Angle Class II division 1 cases, with crowding and bimaxillary protrusion).
- •Fully erupted permanent teeth (except third molar).
- •Age 13-20 patients.
- •No previous orthodontic treatment.
- •Good oral and general health.
- •No systemic disease or regular medication that could interfere with and/or affect orthodontic teeth movement.
排除标准
- •Patients with impacted canines.
- •Patients with severe crowding.
- •Patients with untreated decay or any endodontic lesions.
- •Patients with thyroid, parathyroid, or renal and liver disease.
研究组 & 干预措施
patients will receive local application of vitamin D3 combined with corticision
patients will receive local application of vitamin D3 combined with corticision
干预措施: patients will receive local application of vitamin D3 combined with corticision (Drug)
Control
patients will receive conventional treatment
结局指标
主要结局
Rate of canine retraction
时间窗: baseline to 3 months after initiation of canine retraction
The linear distance of canine movement (in millimeters) was measured from a fixed reference point on dental casts or digital models at baseline and monthly intervals to determine the acceleration effect of local vitamin D3 administration and cortisone.
次要结局
- evaluate the changes in the alveolar bone density(baseline to 3 months after initiation of canine retraction)
研究者
Mahmoud Elsaid
MSc Student in Orthodontics
Al-Azhar University