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Internet Administered CBT for Insomnia Comorbid With Chronic Pain

Not Applicable
Completed
Conditions
Insomnia Due to Medical Condition
Chronic Pain
Registration Number
NCT03425942
Lead Sponsor
Linkoeping University
Brief Summary

Cognitive behavioural therapy (CBT), that is designed to be short, concise and user friendly is compared to applied relaxation techniques as treatment for insomnia comorbid with chronic pain. Both treatments are administered via internet and participants are randomized to ether treatment arm.

Detailed Description

Internet treatment with therapist support means that measurements are collected through the Internet. Participants are recruited from a specialized pain clinic for chronic pain. All patients with sleep complaints (Insomnia Severity Index \> 14) at their first visit through 2016-01-01 to 2017-07-31 are asked for participation via mail. Volunteers sign informed consent and undergo a online screening. If matching the inclusion criteria, they are contacted for a telephone interview. Subjects are assessed according to the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5) criterion for insomnia disorder, M.I.N.I. (screening for psychiatric comorbidity) and the other inclusion/exclusion criteria. The treatment, that is designed to be short, concise and user friendly as it is meant to be usable as an adjunct treatment to other main interventions for chronic pain. The treatment lasts for five weeks and focuses on the most potent CBT technics for insomnia; sleep restriction and stimulus control.

Randomization is conducted by university staff not otherwise involved in this study. Participants have equal chance to be allocated to ether CBT or applied relaxation techniques (active controls). The relaxation treatment lasts for the same amount of time (five weeks) and is designed to require similar weekly effort. Both groups fill in sleep diaries every week and weekly feedback is provided by master students supervised by clinical psychologists.

The overall hypothesis is that CBT leads to greater symptom reduction (according to the Insomnia Severity Index) compared to applied relaxation techniques.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
54
Inclusion Criteria
  • Insomnia severity index (ISI) score > 14
  • Chronic pain
Exclusion Criteria
  • Shift worker or employed as a driver, operator of dangerous equipment and such
  • Sleep apnea, restless legs syndrome, narcolepsy, Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS)
  • Bipolar disorder, psychotic disorders, ongoing substance abuse
  • Having received CBT for insomnia during the latest year
  • Pregnancy
  • Severe somatic disorder (such as ongoing cancer, severe neurological condition, insufficiently treated cardiac condition)
  • Impaired movement to such a degree that going to bed or getting out of bed requires assistance
  • Not being able read or wright in Swedish
  • Not having an internet-connected computer, cellular phone or tablet

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Primary Outcome Measures
NameTimeMethod
Insomnia Severity Index (ISI)Change from baseline insomnia severity (ISI) at 6 months

Measures degree of insomnia. Range 0-28 where a higher value indicates worse sleep.

Secondary Outcome Measures
NameTimeMethod
Pain intensity (NRS)Change from baseline pain intensity (NRS) at 6 months

Eleven stepped numeric rating scale (NRS) for average pain last seven days. Higher values indicate higher pain intensity.

Patient Health Questionnaire (PHQ-9)Change from baseline health (PHQ-9) at 6 months

Measures depressive symptoms. Range 0-27, where a higher value indicates more depressive symptoms.

Pain Disability Index (PDI)Change from baseline disability (PDI) at 6 months

Quantifying pain related disability. Range 0-70 where a higher value indicates more disability.

Sleep diaryDaily during treatment (five weeks).

Basis for sleep latency, total sleep time, wake time after sleep onset and sleep efficiency.

The Karolinska Sleepiness Scale (KSS)Change from baseline sleepiness (KSS) at 5 weeks

Measures sleepiness on a single item numeric rating scale. Range 1-9, where a higher value indicates more sleepiness.

Generalised Anxiety Disorder 7-item scale (GAD-7)Change from baseline anxiety (GAD-7) at 6 months

Measures anxiety symptoms. Range 0-21 where a higher value indicates more anxiety.

Trial Locations

Locations (1)

Rehabilitation medicine, IMH, Linköping University

🇸🇪

Linköping, Östergötland, Sweden

Rehabilitation medicine, IMH, Linköping University
🇸🇪Linköping, Östergötland, Sweden

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