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Clinical Trials/NCT07351253
NCT07351253
Recruiting
Not Applicable

Analgeisc Effect of Erector Spinae Plane Block Versus Lateral Transversus Abdominis Plane Block in Patients Undergoing Open Abendectomy Surgery: a Randomized Controlled Trial

Cairo University1 site in 1 country68 target enrollmentStarted: January 25, 2026Last updated:

Overview

Phase
Not Applicable
Status
Recruiting
Enrollment
68
Locations
1
Primary Endpoint
Total morphine consumption

Overview

Brief Summary

this aim of this study is to compare the analgesic effect of Erector spinae plane (ESP) block and lateral transversus abdominis plan (TAP) block in patients undergoing open appendectomy.

Detailed Description

regional technique according to randomization will be given after induction of general anesthesia Fentanyl boluses of 1 mcg/kg will be given in case of inadequate analgesia. Inadequate analgesia identified by 20% increase in the heart rate and/or systolic blood pressure from baseline measurement.

postoperative analgesia: regular paracetamol 1 g/6 hours (intravenously at first then orally once the oral feeding is resumed) and 75 mg diclofenac (intramuscularly at first then orally once the oral feeding is resumed).

If Numeric rating scale (NRS) is > 3 intravenous titration of 2 mg morphine is given slowly to be repeated after 30 minutes if pain persisted

Study Design

Study Type
Interventional
Allocation
Randomized
Intervention Model
Parallel
Primary Purpose
Prevention
Masking
Triple (Participant, Investigator, Outcomes Assessor)

Eligibility Criteria

Ages
21 Years to — (Adult, Older Adult)
Sex
All
Accepts Healthy Volunteers
No

Inclusion Criteria

  • adult patients, undergoing open appendectomy.

Exclusion Criteria

  • American society of anesthesiologist-physical status \>III,
  • allergy to any of the study drugs,
  • coagulopathy
  • local infection,
  • history of chronic pain or regular opioid use;
  • inability to comprehend the Numeric Rating Scale (NRS),
  • pregnant or lactating women.

Arms & Interventions

ESP group

Active Comparator

Intervention: Erector Spinae Plane Block (Other)

TAP group

Active Comparator

Intervention: Transversus abdominis plane (TAP) block (Other)

Outcomes

Primary Outcomes

Total morphine consumption

Time Frame: from extubation until 24 hours postoperative

mg

Secondary Outcomes

  • numeric rating scale(AT 0.5, 2, 6, 12, and 24 hours postoperative.)
  • quality of recovery(24 hours after suregry)

Investigators

Sponsor Class
Other
Responsible Party
Principal Investigator
Principal Investigator

Ahmed Hasanin

Professor

Cairo University

Study Sites (1)

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