Clinical prospective study to evaluate the efficacy of hygienical therapy and metronidazole in addition to antibiotic therapy in patients affected by bisphosponate-associated osteonecrosis of the jaws - CH.MAX-FACC.02/2009

AZIENDA OSPEDALIERA DI BOLOGNA POLICLINICO S. ORSOLA M. MALPIGHI0 个研究点开始时间: 2010年7月13日最近更新: 2014年2月24日

试验速览

暂无简介。

•Patients with a history of present or previous (interrupted within 10 years) bisphosphonate therapy and diagnosis of osteonecrosis of the jaws. Males or females. Adult patients (more than 18 years old) Patients without pathologies which contraindicate the antibiotic therapy. Patients who have signed the informed consent. Patients who can understand the conditions of the present study and participate for its whole duration.
•Are the trial subjects under 18? no
•Number of subjects for this age range:
•F.1.2 Adults (18-64 years) yes
•F.1.2.1 Number of subjects for this age range
•F.1.3 Elderly (>=65 years) yes
•F.1.3.1 Number of subjects for this age range

•Poor compliance to oral hygiene after experimenter s motivation. Patients affected by patologies who contraindicate the antibiotic therapy. Patients who cannot follow the hygienical procedures indicated in the present protocol nor sign the informed consent. Not-collaborating patients. Known or suspected hypersensitivity towards the drug or the drug class studied. Patients affected by severe clinical conditions which, in experimenter s opinion, contraindicate their participation in the present study.

发起方

AZIENDA OSPEDALIERA DI BOLOGNA POLICLINICO S. ORSOLA M. MALPIGHI