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nravelling the aetiology of pyloric stenosis; a role for the COL3A1 gene?

Conditions
infantile hypertrophic pyloric stenosis
pyloric stenosis
10018008
Registration Number
NL-OMON34013
Lead Sponsor
Academisch Medisch Centrum
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Pending
Sex
Not specified
Target Recruitment
25
Inclusion Criteria

Infants diagnosed with pyloric stenosis, undergoing a pylorotomy.

Exclusion Criteria

Infants diagnosed with pyloric stenosis who already underwent a pylorotomy.
Non-Caucasians

Study & Design

Study Type
Observational invasive
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
<p>Primary outcome:<br /><br>The occurrence of mutations or polymorphisms of the COL3A1 gene in patients<br /><br>with pyloric stenosis</p><br>
Secondary Outcome Measures
NameTimeMethod
<p>Secundary outcome:<br /><br>- the results of Collagene IIIa protein analysis in patients with pyloric<br /><br>stenosis<br /><br>- the clinical characteristics of patients with pyloric stenosis and their<br /><br>relatives</p><br>
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