Evaluation of Patients With Vena Cava Inferior Thrombosis

Completed

• Conditions: Venous Thromboembolism; Inferior Vena Cava Thrombosis

• Registration Number: NCT00631423
• Lead Sponsor: Johann Wolfgang Goethe University Hospital

Brief Summary

The purpose of the study is to evaluate patients with inferior vena cava (IVC)thrombosis in terms of etiology, clinical course and prognosis during long-term follow-up. Patients with isolated lower extremity DVT, matched for age and gender, serve as controls.

Detailed Description

All Patients are assessed using a standardized questionnaire and details concerning VTE risk factors, concomitant disease, medical conditions, diagnosis and therapy of IVC thrombosis were registered. A blood sample is taken to test for inherited and acquired thrombophilia. In addition, duplex ultrasound examination and digital photoplethysmograph are performed to assess postthrombotic syndrome.

Study Timeline

• Study Start: 2007-07
• Study First Submitted: 2008-02-27
• Study First Submitted QC: 2008-02-27
• Study First Posted: 2008-03-07
• Primary Completion: 2014-04
• Study Completion: 2014-08
• Status Verified: 2015-04
• Last Update Submitted: 2015-04-14
• Last Update Posted: 2015-04-15

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 120

Inclusion Criteria

• age 18-90 years

Exclusion Criteria

• none

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Recurrent venous thromboembolism	6, 12, 24 and 60 months

Secondary Outcome Measures

Name	Time	Method
All-cause mortality	6, 12, 24 and 60 months
Post-thrombotic syndrome	24 and 60 months

Trial Locations

Locations (1)

Division of Vascular Medicine, Department of Internal Medicine, J.W.Goethe University Hospital Frankfurt; 🇩🇪 Frankfurt/Main, Hessen, Germany