Metabolic consequences of conjugated linoleic acid supplementation in overweight and obese subjects.
Not Applicable
- Conditions
- E66Obesity
- Registration Number
- DRKS00010462
- Lead Sponsor
- Department of Pediatric Gastroenterology and Metabolic DiseasesPoznan University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- Female
- Target Recruitment
- 74
Inclusion Criteria
1. Female sex
2. Age greater than 18 years
3. Body mass index (BMI) = 25 kg/m2
Exclusion Criteria
1. A history of chronic systemic disease (with the exception of hypertension).
2. Celiac disease.
3. Type 2 diabetes.
4. Pancreatic and/or liver diseas.
5. Current or recent (within the preceding month) treatment with CLA or agents interfering with fat digestion and/or absorption (chitosan, orlistat, green tea)
6. Pregnancy
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Starch and lipid digestion assessed by a starch breath test and a mixed triglyceride breath test at study begin and after twelve weeks of nutritional intervention
- Secondary Outcome Measures
Name Time Method Body weight, body composition(assessed by dual-energy X-ray absorptiometry (DXA), total energy expenditure (assessed by 13C bicarbonate<br>sodium breath test), liver metabolism (assessed by 13C methacetin breath test), mineral status (assessed in 24-hour urine collection<br>and in hair samples), blood lipid profile, polyunsaturated fatty acids blood profile; all secondary outcomes were measured at the study begin and after nutritional intervention