Correlation Between qNOX Values of the CONOX Monitor and Analgesia Nociception Index (ANI) Values During General Anesthesia Conducted With Propofol and Remifentanil TCI
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 15
- 试验地点
- 1
- 主要终点
- Correlation between qNOX and ANI values
研究概览
简要总结
qNOX and ANI are two indexes evaluting the analgesia conduction during general anesthesia.
No trials have compared them, so with this trial authors want to explore the correlations between them.
详细描述
qNOX and ANI are two indexes evaluting the anaglesia conduction during general anesthesia.
Even if the aim is the same (to measure the nociception level) these indexes utilize different algorithm: the qNOX is derived by the electroencephalogrm (EEG), the ANI is derived by heart rate variation.
No trials have compared them, so with this trial authors want to explore the correlations between them, and if altered values of one of them is stronger related to postoperative pain and delirium.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 90 Years（Adult, Older Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •Undergo general anaesthesia with Targeted Controlled Infusion of Propofol (Eleveld model) and remifentanil (Eleveld model)
排除标准
- •Neurological disease
- •Psychiatric disease
- •Regional anesthesia performed
结局指标
主要结局
Correlation between qNOX and ANI values
时间窗: qNOX, ANI, pupoillometry values, propofol and remifentanil concentration during induction, intubation, after post-tetanic count at the trend-of-four and maintenance phase of general anesthesia detected with target controlled inusion will be paired.
qNOX and ANI values will be compared to check the correspondance in evaluting analgesia level
次要结局
- Correlation between qNOX from CONOX and analgesia nocicpetion index (ANI) values and postoperative delirium(qNOX, ANI and remifentanil concentrations recorded during induction, intubation and maintenance phase of general anesthesia will be related to postoperative delirium, evaluated with CAM and 4AT score after 24 hours)
- Correlation between qNOX from CONOX and Analgesia nocicpetion index (ANI) values and postoperative pain(qNOX, ANI and remifentanil concentrations recorded during induction, intubation and maintenance phase of general anesthesia will be related to postoperative pain, evalued with NRS score after 24 hours)
研究者
Federico Linassi
MD, principal invesigator
University of Padova