oxidative stress and attention in epilepsy

Not Applicable

• Conditions: Genetic Diseases; Mental and Behavioural Disorders; Paediatrics; epilepsy

• Registration Number: PACTR201801002991130
• Lead Sponsor: ational Research Center, Giza, Egypt.

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2018-01-20
• Last Update Posted: 29 May 2023

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

case group: Children with idiopathic epilepsy
Aged 6-15 years

control group: healthy age and sex matched children

Exclusion Criteria

Children with any acute or chronic medical illness
Children with mental retardation
children with hearing impairment
children with any concomitant psychological disorders
Children with developmental delay
Children with physical disabilities
children received any medications affecting cognitive function as antihistamines

control group: fullfil the same exclusion criteria and did not have any history of neurological disorders, seizures or family history of epilepsy

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
assess the association between malonaldhyde level as marker of oxidative stress and selective attention assessed by p300 auditory event related potential in children with idiopathic epilepsy;assess the association between clinical characterestics of epilepsy and the serum level of malonaldhyde oxidative marker and auditory event related potential

Secondary Outcome Measures

Name	Time	Method
assess the association between clinical characterestics of epilepsy and the serum level of malonaldhyde oxidative marker and auditory event related potential;assess the impact of proper siezure control on both oxidative stress and selective attention