Transthoracic Sonography Versus High Resolution Computed Tomography in Alveolar Intersitial Syndrome

Not Applicable

• Conditions: Pleural Diseases
• Interventions: Other: High resolution computed tomography; Other: trans thoracic ultrasonography

• Registration Number: NCT03172585
• Lead Sponsor: Assiut University

Brief Summary

High resolution computed tomography of the chest is the gold standard imaging modality for most pulmonary diseases. However, the associated high expenses, radiation exposure , and its limited possibility for bedside use are a limitation.

Detailed Description

High resolution computed tomography of the chest is the gold standard imaging modality for most pulmonary diseases. However, the associated high expenses, radiation exposure , and its limited possibility for bedside use are a limitation. Transthoracic ultrasonograghy is used progressively for evaluation of pulmonary diseases. Its non invasive nature , relatively low price ,portability for bedside use, and high reproducibility of results allows for incorporation of imaging findings with clinical data. Although Transthoracic ultrasonograghy is not an alternative to High resolution computed tomography,it can potentially provide useful supplemental information in certain specific situations ,such as for rapid bedside diagnostic assessment of dyspneic patients. B-line is a common and significant abnormal sign used for diagnostic appraisal by Transthoracic ultrasonograghy, but it cannot define the exact underlying pathologic feature on a lung ultrasound. When the lung parenchymal pathology reaches the lung surface ,certain characteristic changes of the pleural line can be detected by means of the good imaging made possible by high-resolution Transthoracic ultrasonograghy ,but the application and strength of pleural line abnormalities in the differential diagnosis of lung diseases has not been adequately explored . Existing literature on the illustration of the pleural line is scarce ,and the shape of pleural line has not been adequately investigated and described ,especially in comparison with Computed tomography findings. Most studies that have investigated pleural lines are confined to the sub population with interstitial lung diseases.

Study Timeline

• Status Verified: 2017-05
• Study First Submitted: 2017-05-26
• Study First Submitted QC: 2017-05-30
• Last Update Submitted: 2017-05-30
• Study Start: 2017-06
• Study First Posted: 2017-06-01
• Last Update Posted: 2017-06-01
• Primary Completion: 2018-06
• Study Completion: 2018-08

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 1

Inclusion Criteria

1. Patients presenting with dyspnea due to interstitial fibrosis syndrome.
2. pulmonary edema due to any cause.

Exclusion Criteria

1. Traumatic lesions
2. Pneumothorax
3. Subcutaneous emphysema
4. Massive pleural effusion with atelectasis, and

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
High Resolution computed tomography	High resolution computed tomography	Patients will be included in the study when High resolution chest computed tomography without contrast enhancement is ordered by the primary physician. Before the High resolution chest computed tomography scan, a Trans thoracic ultrasonography will be performed.
High Resolution computed tomography	trans thoracic ultrasonography	Patients will be included in the study when High resolution chest computed tomography without contrast enhancement is ordered by the primary physician. Before the High resolution chest computed tomography scan, a Trans thoracic ultrasonography will be performed.

Primary Outcome Measures

Name	Time	Method
the number of patients diagnosed with pleural diseases by high resolution computed tomography	30 minutes	computed tomography on the chest