ong-term noninvasive ventilation or oxygen therapy in patients with severe stable COPD: a multicenter observational study
Not Applicable
Recruiting
- Conditions
- Chronic Obstructive Lung disease
- Registration Number
- JPRN-UMIN000015615
- Lead Sponsor
- Graduate School of Medicine, Kyoto University Department of Respiratory Care and Sleep Control Medicine
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 60
Inclusion Criteria
Not provided
Exclusion Criteria
1) pH <7.30 in ABG 2) current smoking 3) strongly suspected for sleep apnea (4%ODI [oxygen desaturation index 4%] >20) 4) chronic use of systemic glucocorticosteroids 5) pneumothorax in the previous 6 months 6) having other chronic pulmonary disease 7) clinically obvious heart failure 8) acute infection or malignancy 9) previous or current use of LTOT or NIV 10) pregnancy or lactation 11) other cases not suitable for the study
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Changes in PaO2 (oxygen group) or PaCO2 (NIV group) before and after the treatment
- Secondary Outcome Measures
Name Time Method 1) Pulmonary function test 2) exercise tolerance (assessed by 6MWT) 3) physical activity (assessed by accelerometer) 4) Health-related QOL 5) Exacerabtions of COPD 6) Mortality