on-invasive ventilation (NIV) as an aid to rehabilitation in acute respiratory disease
Completed
- Conditions
- Other chronic obstructive pulmonary diseaseAcute exacerbation of chronic obstructive pulmonary disease (COPD)Respiratory
- Registration Number
- ISRCTN35692743
- Lead Sponsor
- Imperial College London (UK)
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 45
Inclusion Criteria
1. Adult patient admitted with an acute exacerbation of COPD
2. Expected to be in hospital for at least 24 hours
Exclusion Criteria
1. Patients who are not expected to survive the admission
2. Patients with significant co-morbidity which is thought to be the major factor limiting their exercise capacity
3. Inability to understand instructions or use an exercise bike
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Quadriceps strength measured as quadriceps isometric maximum voluntary contraction force using a dynamometer at 2 weeks after discharge.
- Secondary Outcome Measures
Name Time Method 1. COPD Assessment Test (CAT) score<br>2. St George's Respiratory Questionnaire (SGRQ)<br>3. Physical activity monitored with SenseWear armband<br>4. Acceptability of treatment<br>5. Incremental shuttle walk test distance<br>All secondary outcomes will be assessed at baseline, discharge from hospital and 2 weeks post discharge.