Pre-hospital use of non-invasive ventilation improves acute respiratory failure
Completed
- Conditions
- Acute respiratory failureRespiratoryRespiratory failure, not elsewhere classified
- Registration Number
- ISRCTN47620321
- Lead Sponsor
- Medical Service of the Bundeswehr (Sanitätsamt der Bundeswehr [SanABw]) (Germany)
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 30
Inclusion Criteria
Pre-hospital patients:
1. Aged above 18 years, either sex
2. Acute dyspnoea
3. Respiratory rate greater than 25/min
4. Pulse oxymetric oxygen saturation less than 90%
Exclusion Criteria
1. Refusal of NIV
2. Vomiting
3. Glasgow Coma Scale less than 12 points
4. Suspected myocardial ischaemia
5. Systolic blood pressure less than 100 mmHg
6. Pregnancy
7. Injury of face or neck
8. Participation in another study
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Rate of endotracheal intubation during first 24 hours of treatment.
- Secondary Outcome Measures
Name Time Method 1. Difference of baseline and admission values of:<br>1.1. Pulse oxymetric oxygen saturation <br>1.2. Respiratory rate<br>1.3. Dyspnoea score<br>1.4. Heart rate<br>1.5. Systolic diastolic arterial blood pressure<br>2. Duration of intensive care<br>3. Incidence and duration of mechanical ventilation, and hospital days <br>4. Feasibility of NIV was rated at a scale from 1 to 5 (very good, good, acceptable, difficult, not feasible)