Study on Corneal and Eye Surface Changes in South Indian Diabetic Wome
Not Applicable
- Conditions
- Health Condition 1: H188- Other specified disorders of cornea
- Registration Number
- CTRI/2023/04/051235
- Lead Sponsor
- Investigator initiated study
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1. Female subjects with diabetes.
2. Patients above the age of 30 years
Exclusion Criteria
1. Previous history of lid injury.
2. Previous history of lid surgeries.
3. Previous history of intraocular surgery.
4. Patients diagnosed glaucoma on topical medication.
5. Previous history of intraocular or periocular injections.
6. Patients with ptosis, lagophthalmos, altered corneal sensation.
7. Patients with active ocular inflammation or any corneal pathologies.
8. Past history of joint pain, rheumatoid arthritis, autoimmune disorders.
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1. Corneal thickness measurements would be determined by use of an ultrasonic pachymeter <br/ ><br>2. Staining characteristics with Rose Bengal and Fluorescein <br/ ><br>3. Corneal sensitivity <br/ ><br>4. Schirmerâ??s test <br/ ><br>5. Tear film characteristics <br/ ><br>6. Biomicroscopy <br/ ><br>Timepoint: Baseline, Month-06 & Month-12 <br/ ><br>
- Secondary Outcome Measures
Name Time Method 1. HbA1C <br/ ><br>2. Culture for microorganisms <br/ ><br>3. Meibomian gland morphology <br/ ><br>4. Corneal endothelial cell count would be done using specular microscope <br/ ><br>5. Optical Coherence Tomography (OCT)Timepoint: Baseline & Month-12