Determinants of the Effectiveness of Robot-assisted Hand Movement Training
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
- 入组人数
- 60
- 试验地点
- 2
- 主要终点
- Box and Blocks Test
研究概览
简要总结
The investigators would like to investigate the effectiveness of somatosensory training for robot-assisted hand motor rehabilitation after stroke.
详细描述
From previous studies, the investigators learned that stroke survivors with impaired finger proprioception did not achieve as large a functional benefit from robotic finger training. For this study, the investigators would like to determine if and the extent of finger proprioception can be improved through targeted robotic proprioceptive training combined with robotic finger movement training. The investigators would also include imagining studies via Electroencephalogram (EEG) and other baseline predictors to provide insight to determine who responds best to proprioceptive training.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Outcomes Assessor)
盲法说明
Randomized single-blinded
入排标准
- 年龄范围
- 18 Years 至 85 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age 18 to 85 years
- •Suffered from a single ischemic stroke (radiologically confirmed) at least 6-months prior to enrollment
- •An ability to score at least 3 blocks on the Box and Block Test
排除标准
- •A substantial decrease in alertness, language reception or attention
- •Pregnant or lactating
- •Advanced liver, kidney, cardiac or pulmonary disease
- •Plan to alter any current participation in other rehabilitation therapy in the time period of the study
- •A terminal medical diagnosis consistent with survival < 1 year
- •Coexistent major neurological disease
- •Coexistent major psychiatric disease
- •A history of significant alcohol or drug abuse in the prior 3 years
- •Current enrollment in another study related to stroke or stroke recovery
- •Any other medical contraindication to participation in this study evaluated by our team physician.
结局指标
主要结局
Box and Blocks Test
时间窗: From baseline to 1-month post intervention
We compare the change of Box and Block Test scores from baseline evaluation to 1-month post intervention. Participants are instructed to move as many blocks as possible, one at a time, from one compartment in a box to a second compartment over a divider for a period of 60 seconds; each block that is moved is counted, and multiple blocks moved at the same time are counted as a single block. The higher scores indicate a better outcome.
次要结局
- Motor Activity Log(From baseline to 1-month post intervention)
- Changes in finger proprioception measured using the Crisscross Assessment.(From baseline to 1-month post intervention)
- Fugl-Meyer Motor Assessment of the Upper Extremity(From baseline to 1-month post intervention)
研究者
David Reinkensmeyer
Professor
University of California, Irvine