Effect of Various Forms of Upper Body Exercise on the Energetic Response to a Meal in Persons With Spinal Cord Injury
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 10
- 试验地点
- 1
- 主要终点
- Postprandial insulin sensitivity
研究概览
简要总结
This study investigates the effect of various forms of upper extremity exercise on postprandial glycemia and lipemia in persons with spinal cord injury (SCI). Participants are measured at rest and fed a standardized meal following seated rest (CON), moderate intensity continuous arm cycling (MICT), high intensity interval arm cycling (HIIT), and circuit resistance exercise (CRT) matched for exercise energy expenditure.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Factorial
- 主要目的
- Prevention
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Adult (>/=18 years of age)
- •Neurologically stable chronic (>/= 1year) spinal cord injury (SCI)
- •American Spinal Injury Association Impairment Scale (AIS) grade A, B, or C
- •SCI at level </= the first thoracic vertebrae (T1)
排除标准
- •Being of ≤ 18 years of age.
- •Contraindication to exercise (ACSM Guideline, 10th edition)
- •Lower extremity fracture or dislocation within 6 months of participation,
- •History head injury or seizures.
- •Inability to consent.
- •Restrictions in upper extremity range of motion that would prevent an individual from achieving an unhindered arm cycling motion or moving throughout a range needed to perform resistance maneuvers.
- •A pressure ulcer at ischial/gluteus, trochanteric, sacral, or heel sites within the last 3 months.
- •Pregnancy determined by urine testing in sexually active females.
- •Imprisonment in state or federal jail or prison.
研究组 & 干预措施
High intensity interval training (HIIT)
Participants complete interval arm cycling at power output that varies between 2 min "active" and two min "recovery" periods. This interval exercise is matched to the total energy expenditure (accumulated kcals) response during CRT. Following the intervention they are fed.
干预措施: High intensity interval training (HIIT) (Behavioral)
High intensity interval training (HIIT)
Participants complete interval arm cycling at power output that varies between 2 min "active" and two min "recovery" periods. This interval exercise is matched to the total energy expenditure (accumulated kcals) response during CRT. Following the intervention they are fed.
干预措施: Liquid Meal (Other)
Seated control (CON)
Participants remain seated in their habitual wheel chair for ~45 min (duration of exercise performed in other arms). Following the intervention they are fed.
干预措施: Seated control (CON) (Behavioral)
Seated control (CON)
Participants remain seated in their habitual wheel chair for ~45 min (duration of exercise performed in other arms). Following the intervention they are fed.
干预措施: Liquid Meal (Other)
Circuit resistance training (CRT)
Participants complete upper extremity resistance maneuvers (lifts) interspersed with low-load/high-speed arm cycling for a combined 30 repetitions of 6 lifts and ~20 min of arm cycling. During this time energy expenditure is measured via open-circuit indirect calorimetry. Following the intervention they are fed.
干预措施: Circuit resistance training (CRT) (Behavioral)
Circuit resistance training (CRT)
Participants complete upper extremity resistance maneuvers (lifts) interspersed with low-load/high-speed arm cycling for a combined 30 repetitions of 6 lifts and ~20 min of arm cycling. During this time energy expenditure is measured via open-circuit indirect calorimetry. Following the intervention they are fed.
干预措施: Liquid Meal (Other)
Moderate intensity continuous (MICT)
Participants complete continous arm cycling at a steady-state power output (intensity) matched to the energy expenditure (kcal/min) and duration of exercise (min) response during CRT. Following the intervention they are fed.
干预措施: Moderate intensity continuous (MICT) (Behavioral)
Moderate intensity continuous (MICT)
Participants complete continous arm cycling at a steady-state power output (intensity) matched to the energy expenditure (kcal/min) and duration of exercise (min) response during CRT. Following the intervention they are fed.
干预措施: Liquid Meal (Other)
结局指标
主要结局
Postprandial insulin sensitivity
时间窗: 2.5 hr
Measured by insulin incremental area under the curve (iAUC).
次要结局
- Lipemia(2.5 hr)
- Carbohydrate use(2.5 hr)
- Fasted insulin sensitivity(Baseline)
- Fat use(2.5 hr)
研究者
Mark S. Nash, Ph.D., FACSM
Professor
University of Miami