PAmidronate for Pain in Sternocostoclavicular hyperostosis: the PAPS-study, a double-blind randomized placebo-controlled trial
- Conditions
- Inflammation of sternal region, Sternocostoclavicular hyperostosisTherapeutic area: Diseases [C] - Musculoskeletal Diseases [C05]Therapeutic area: Diseases [C] - Skin and Connective Tissue Diseases [C17]
- Registration Number
- CTIS2023-510309-16-00
- Lead Sponsor
- Academisch Ziekenhuis Leiden
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 70
NRS score for maximal pain of = 6/10 at lesion sites, Signs of disease activity on imaging at lesion sites, No treatment with bisphosphonates for the previous 6 months
Age below 18 years of age, Mental disability, Active pregnancy wish, pregnancy or nursing, Generalized pain without CNO related pain, Bisphosphonate allergy, Estimated glomerular filtration rate < 30 ml/min, Uncontrolled endocrine abnormalities, Active cancer treatment, Language barrier, Severe co-morbidity, including poor mobility and other causes preventing attendance for control visits
Study & Design
- Study Type
- Interventional clinical trial of medicinal product
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.