Stellate Ganglion Block

Phase 4

Not yet recruiting

• Conditions: Lobectomy; Esophagectomy; Pneumonectomy
• Interventions: Drug: 0.5% bupivacaine; Other: Saline

• Registration Number: NCT06271707
• Lead Sponsor: University of Minnesota

Brief Summary

The purpose of this study is to determine if the addition of an ultrasound guided left sided stellate ganglion block with bupivacaine in patients undergoing esophagectomy, pneumonectomy, or lobectomy will result in lower rates of postoperative atrial fibrillation as compared to standard of care.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2024-02-14
• Study First Submitted QC: 2024-02-14
• Study First Posted: 2024-02-22
• Status Verified: 2025-05
• Last Update Submitted: 2025-05-07
• Last Update Posted: 2025-05-08
• Study Start: 2025-05-15
• Primary Completion: 2027-04-15
• Study Completion: 2027-07-15

Recruitment & Eligibility

• Status: NOT_YET_RECRUITING
• Sex: All
• Target Recruitment: 48

Inclusion Criteria

• Patients undergoing esophagectomy, pneumonectomy, or lobectomy aged 18-85.

Exclusion Criteria

• Patients who have an exclusion to regional anesthesia.
• Patients who have exclusion to stellate blockade.
• Patients who are pregnant assessed via self-report or pregnancy test if they have taken one

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Group 1	0.5% bupivacaine	ultrasound with bupivacaine
Group 2	Saline	Ultrasound with saline

Primary Outcome Measures

Name	Time	Method
an ultrasound guided left stellate ganglion block with 5 mL of saline.	168 hours after surgery	Incidence of Atrial fibrillation in the first 168 hours after surgery.
Atrial fibrillation; Other arrhythmias; Adverse events.	168 hours after surgery	Atrial fibrillation in first 24, 48, 72, 96, 120, and 144 hours; Other arrhythmias in first 24, 48, 72, 96, 120, 144 and 168 hours; Adverse events.