Left Sided Stellate Ganglion Blocks Impact on the Rate of Post-operative Atrial Fibrillation in Patients Undergoing Thoracic Surgery: A Pilot Study
Overview
- Phase
- Phase 4
- Status
- Recruiting
- Sponsor
- University of Minnesota
- Enrollment
- 48
- Locations
- 1
- Primary Endpoint
- an ultrasound guided left stellate ganglion block with 5 mL of saline.
Overview
Brief Summary
The purpose of this study is to determine if the addition of an ultrasound guided left sided stellate ganglion block with bupivacaine in patients undergoing esophagectomy, pneumonectomy, or lobectomy will result in lower rates of postoperative atrial fibrillation as compared to standard of care.
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Parallel
- Primary Purpose
- Prevention
- Masking
- Triple (Participant, Investigator, Outcomes Assessor)
Masking Description
This is a double blind randomized prospective controlled trial. Randomization will be 1:1.
Eligibility Criteria
- Ages
- 18 Years to 85 Years (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •Patients undergoing esophagectomy, pneumonectomy, or lobectomy aged 18-85.
Exclusion Criteria
- •Patients who have an exclusion to regional anesthesia.
- •Patients who have exclusion to stellate blockade.
- •Patients who are pregnant assessed via self-report or pregnancy test if they have taken one
Arms & Interventions
Group 1
ultrasound with bupivacaine
Intervention: 0.5% bupivacaine (Drug)
Group 2
Ultrasound with saline
Intervention: Saline (Other)
Outcomes
Primary Outcomes
an ultrasound guided left stellate ganglion block with 5 mL of saline.
Time Frame: 168 hours after surgery
Incidence of Atrial fibrillation in the first 168 hours after surgery.
Atrial fibrillation; Other arrhythmias; Adverse events.
Time Frame: 168 hours after surgery
Atrial fibrillation in first 24, 48, 72, 96, 120, and 144 hours; Other arrhythmias in first 24, 48, 72, 96, 120, 144 and 168 hours; Adverse events.
Secondary Outcomes
No secondary outcomes reported