Validation of a non-invasive measured surrogate parameter for craniospinal compliance by measuring the electrical capacity of the head

Recruiting

• Conditions: G91.0; G97.0; Communicating hydrocephalus; Cerebrospinal fluid leak from spinal puncture

• Registration Number: DRKS00022513
• Lead Sponsor: niklinik Freiburg - Klinik für Neurochirurgie

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2020-07-27
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 180

Inclusion Criteria

Suspicion of the presence of a liquor circulation disturbance.

Exclusion Criteria

Plaster allergy (possible skin irritation caused by the electrodes), and patients unable to give consent.

Study & Design

• Study Type: observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Respiratory Amplitude Coefficient (RAQ)

Secondary Outcome Measures

Name	Time	Method
clinical parameters of gait disorders, spatial impairment, cognitive abilities, urinary incontinence, pain caused by headache, visual acuity, parameters of the computerized lumbar infusion test (baseline CSF pressure, pressure-volume index, pulse amplitude), documented intracranial pressures, cell count and total protein in CSF, diameter of the sonographic optic nerve sheath (ONSD), radiological findings. <br>Age and sex of study participants, BMI, height, presence of comorbidities based on the Charlson comorbidity index (CCI) <br>previous cranial operations, presence of cranial implants.<br>The parameters are collected at the initial examination and, in patients with CSF circulation disorders, at follow-up examinations (always after 3 months).