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临床试验/NCT05884827
NCT05884827招募中不适用

Peroneal Nerve Dysfunction in Proximal Fibular Epiphyseal Harvesting Cases

Assiut University1 个研究点 分布在 1 个国家目标入组 15 人开始时间: 2023年6月1日最近更新:
适应症

试验速览

阶段
不适用
状态
招募中
入组人数
15
试验地点
1
主要终点
Assessment of Tibialis anterior dysfunction after proximal fibular epiphyseal harvesting

研究概览

简要总结

Assessment of peroneal nerve dysfunction after proximal fibular epiphyseal resection and evaluation of clinical outcome and EMG changes.

详细描述

In children the preserved epiphysis of the proximal fibula ensure the exceptional ability to recover both joint function and longitudinal limb growth at the same time. Traumatic bone defect, congenital malformations, malignant bone lesions and infection are all current indications for VFET. The shape and size of the proximal fibular epiphysis aid in the gradual remodeling of the articular surface, allowing for better reconstruction and eventual rehabilitation over time.

Harvesting the proximal epiphysis of the fibula, along with its intact blood supply, is technically demanding, and the success of VFET is a primarily dependent on restoring adequate vascularity to the growth plate and diaphysis.

Anterior tibial artery is the primary and most consistent contributor to the proximal fibular epiphysis and proximal two thirds of diaphysis, it has intimate connection to the motor (deep) branch of peroneal nerve. The success of anterior tibial artery based VFET based on preserving the anterior tibial Vascular bundle, so it may be necessary to sacrifice some branches of peroneal nerve to tibialis anterior muscle. This is a significant flaw in the approach that could result in permanent peroneal nerve palsy.

研究设计

研究类型
Observational
观察模型
Case Only
时间视角
Prospective

入排标准

年龄范围
18 Months 至 14 Years(Child)
性别
All
接受健康志愿者

入选标准

  • all patients candidate for epiphyseal transfer are included ( patients with traumatic bone defect, congenital malformations, malignant bone lesions and infection )

排除标准

  • patients in which there's no injury of nerve supply of tibialis anterior has occurred intraoperative

结局指标

主要结局

Assessment of Tibialis anterior dysfunction after proximal fibular epiphyseal harvesting

时间窗: Six months

Electromyography changes at 3 weeks , 6 weeks , 3 months and 6 months to assess the affection of tibialis anterior muscle \& peroneal nerve

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Ahmed Moustafa Elsese

Principal investigator

Assiut University

研究点 (1)

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