Assessment of Acute Kidney Injury as a Risk Factor for Myocardial Injury and Ventricular Systolic Dysfunction After Non-Cardiac Surgery in Critical Patients
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 520
- 试验地点
- 1
- 主要终点
- development myocardial injury
研究概览
简要总结
Acute kidney injury (AKI) is classically described as an abrupt or rapidly reversible reduction in the excretion of nitrogenous waste products, including urea, nitrogen and creatinine. Acute kidney injury definition emphasizes on the filtration function of the kidney, a measure that is unique and easily and routinely measured .
Acute kidney injury is associated with significantly increased resource utilization and health care costs.
Major adverse cardiac events (MACE) after non cardiac surgery are a leading cause of morbidity and mortality. The reported incidence of postoperative myocardial infarction (POMI) among patients undergoing non cardiac surgery is between 3% and 6%.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 70 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients with normal kidney functions and free normal heart functions, were enrolled to this study
排除标准
- •patients with chronic kidney disease, cardiac disease, who with minor operations, or emergency, were excluded from the study.
结局指标
主要结局
development myocardial injury
时间窗: through study completion, an average of 15 days
New echocardiographic findings suggestive of ischemia (new regional wall motion abnormalities) or cardiac troponin T \>.0.32 ng/ml
次要结局
未报告次要终点
研究者
Alaa Ali M. Elzohry
4- Lecturer of Anesthesia, ICU and Pain Relief, South Egypt Cancer Institute, Assiut University, Egypt
South Egypt Cancer Institute