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ow dose vitamin K to improve therapeutic quality control of oral anticoagulant treatment: a randomized double-blind placebo controlled trial.

Completed
Registration Number
NL-OMON25820
Lead Sponsor
Trombosestichting Nederland
Brief Summary

J Thromb Haemost. 2007 Oct;5(10):2043-8. Epub 2007 Jul 31.

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
Not specified
Target Recruitment
200
Inclusion Criteria

1. Patients treated at the Leiden anticoagulation clinic with an indication for long-term oral anticoagulant therapy using the vitamin K antagonist phenprocoumon;

2. Age between 18 and 80 years;

Exclusion Criteria

1. Treatment by a medical specialist for liver failure;

2. Haemo- or peritoneal dialysis;

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
1. Quality of anticoagulant treatment;<br /><br>2. Expressed as time in therapeutic range.
Secondary Outcome Measures
NameTimeMethod
1. Number of INRs in therapeutic range;<br /><br>2. Bleeding and thromboembolic complications.
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