NL-OMON40846
Withdrawn
Phase 3
Evaluation of the Safety and Efficacy of Using Insulin-like Growth Factor-1 in Patients With a Heart Attack (RESUS-AMI) - RESUS-AMI
niversity college Cork, Centre for Research in Vascular Biology Bio Sciences Institute0 sites15 target enrollmentTBD
Overview
- Phase
- Phase 3
- Intervention
- Not specified
- Conditions
- acute myocardial infarction with LVEF< 30%
- Sponsor
- niversity college Cork, Centre for Research in Vascular Biology Bio Sciences Institute
- Enrollment
- 15
- Status
- Withdrawn
- Last Updated
- 2 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •1\. Age 18 \* 75
- •2\. Subject presents to hospital within 2\-12 hours of the onset of myocardial ischemic pain of at least 30 minutes duration
- •3\. Twelve\-lead electrocardiogram (ECG) reveals one of the following: ST\-segment elevation \* 0\.1 mV in two or more limb leads, or \* 0\.2 mV in two or more contiguous precordial leads indicative of acute myocardial infarction, or left bundle\-branch block
- •4\. Undergoing PCI for STEMI
- •5\. LVEF during PCI \< 40%
- •6\. TIMI flow grade 3 in IRA following reperfusion and stenting
Exclusion Criteria
- •4\.3 EXCLUSION CRITERIA
- •Subjects having any of the following criteria will not be enrolled in the study:
- •1\. History of prior myocardial infarction
- •2\. Prior history of heart failure, left ventricular dysfunction or cardiomyopathy
- •3\. Active or suspected neoplasia
- •4\. Known impaired liver function
- •5\. Cardiogenic shock (SBP\<80mm Hg requiring pressors or IABP)
- •6\. Estimated glomerular filtration rate (eGFR) \< 45 ml/min/1\.73m2
- •7\. History of hypoglycaemia requiring hospitalisation
- •8\. History of primary insulin growth factor\-1 deficiency or growth hormone disorders including acromegaly
Outcomes
Primary Outcomes
Not specified
Similar Trials
Completed
Not Applicable
usefulness of IPL in treating melasmaCTRI/2017/08/009529IPGMER and SSKM HOSPITA32
Recruiting
Phase 2
Comparison of intracoronary selected CD 133+ bone marrow stem cells in cardiac recovery after acute myocardial infarct and left ventricular dysfunction: COMPARE-AMI a randomized controlled double blind clinical studyACTRN12609001045202Miltenyi Biotech Inc.40
Completed
Not Applicable
A comparative study to know efficacy and safety of IM carbetocin verses IV carbetocin (drug to prevent PPH) in vaginal deliveryHealth Condition 1: O80- Encounter for full-term uncomplicated deliveryCTRI/2023/03/050468DR SWATI TALWADE134
Completed
Phase 2
Assessment of the Results of Inovo Sense Smile and Inovo Sense Style Filler Injections to Correction Nasolabial FoldsIRCT20220723055530N1Khosro Medisa Teb Company30
Recruiting
Not Applicable
The study on the efficacy and safety of combination of low dose propiverine hydrocholoride and alpha-antagonist in men with BPH with overactive bladderDiseases of The genitoruinary systemKCT0000077Inha University Hospital236