Leptospirosis Care Bundle Study
Not Applicable
Recruiting
- Conditions
- Leptospirosis
- Interventions
- Procedure: Care Bundle
- Registration Number
- NCT05425524
- Lead Sponsor
- Chulalongkorn University
- Brief Summary
So in management of Leptospirosis patients There really is no another approach to treatment. The importance of the problem was acknowledged by the researchers. As a result, this study was performed in order to The Leptospirosis Care Bundle has been used, and has been proved that its use can reduce the risk of acute renal failure.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- RECRUITING
- Sex
- All
- Target Recruitment
- 300
Inclusion Criteria
- age > 18 years
- Suspicious Leptospirosis including body temperature > 38 celcius, Severe myalgia, and exposure to reservoir hospital of flood water.
- Calf muscle tenderness
- Conjunctival suffusion
- Anuria or oliguria and/or proteinuria
- Jaundice
- Hemorrhagic manifestations (pulmonary and intestine)
- Meningeal irritation
- Nausea, vomiting, abdominal pain, diarrhea.
- Admitted in hospital
Exclusion Criteria
- other infectious disease
- pregnancy
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Care Bundle Group Care Bundle Treatment step by step we have 5 steps STEP 1: Leptospirosis suspected case STEP 2: Investigations STEP 3: Antibiotics within 1 hour after Hemocultures were taken STEP 4: Intravenous Fluid STEP 5: Stage-Base Management of AKI (KDIGO)
- Primary Outcome Measures
Name Time Method Number of Participants with Reduce AKI in 72 hours 72 hours To see if using care bundle for leptospirosis patients can improve reduce the incidence of acute renal failure in the first 72 hours of being admitted to hospital.It classified AKI into three categories (risk, injury, and failure) according to the status of serum creatinine (SCr) and urine output (UO) by AKIN/KDIGO
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Chulalongkorn university
🇹ðŸ‡Bangkok, Thailand