Effects of WiFi Exposure on Sleep and Sleep Related Memory Consolidation in Young Healthy Women
试验速览
- 阶段
- 不适用
- 状态
- 暂停
- 入组人数
- 34
- 试验地点
- 1
- 主要终点
- Sleep Efficiency index
研究概览
简要总结
Effects of Wifi exposure on sleep and sleep-related memory consolidation are investigated in a double-blind, sham-controlled fully counterbalanced study design in young healthy women.
详细描述
Introduction
Since several years Wireless Local Networks (WLAN, WiFi) are widely spread and operated in households. Many people feel that the presence of radiofrequency technologies impairs their health. Sleep problems are among the most often complained complaints. The present study aims to contribute to answer the question, whether biological effects of a WiFi exposure can be assessed by objective measures. The results of this study will expand the database on possible acute effects of WiFi exposure and thus qualitatively contribute to the discussion whether sleep is affected by exposure from radiofrequency electromagnetic fields.
Methods: A double-blind, sham-controlled experiment in the sleep laboratory with exposure conditions delivered in a balanced randomized cross-over design. Subjective sleep quality of volunteers is assessed by questionnaires. Macro- and microstructure of sleep are measured by polysomnography. Furthermore, a possible impact on sleep related memory consolidation is tested. To do so declarative, procedural and emotional memory tasks are used. Exposure is delivered by a specially developed system, which simulates field strengths and signals occurring in a subject sleeping in the close proximity of a WiFi-access point. This exposure system is necessary to allow for a double-blind implementation and monitoring as well as for the realization of defined exposure parameters.
The study aims to analyse possible sex differences in WiFi exposure effects on sleep and sleep related memory consolidation.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Basic Science
- 盲法
- Triple (Participant, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 20 Years 至 30 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •Only right-handed
- •non-smokers
- •Pittsburgh Sleep Quality Index (PSQI) score < 5
- •no extreme morning/evening preference [Morningness-Eveningness Questionnaire (MEQ) score ≥ 31 or ≤ 69
- •no indication of depression or somatic symptoms as assessed by a medical examination and validated questionnaires [Patient Health Questionnaires (PHQ-9 and PHQ-15) scores ≤ 5 and ≤ 10, respectively
排除标准
- •history of a psychiatric disorder,
- •history of a neurological and/or sleep disorder
- •excessive daytime sleepiness [Epworth Sleepiness Scale (ESS) score > 9;
- •non-regular sleep-wake schedule as assessed by a sleep diary
- •a regular intake of medication that affects the central nervous system, excessive caffeine and/or alcohol consumption, regular and occasional drug use,
- •metal implants
- •periodic leg movement arousal index > 10/h in the Adaptation night
- •apnoea-hypopnoea-index > 5/h in the Adaptation night.
研究组 & 干预措施
Experimental: WiFi - Sham
first intervention WiFi, second intervention sham
干预措施: radio frequency electromagnetic fields (Other)
Experimental: Sham - WiFi
first Intervention sham, second Intervention WiFi
干预措施: radio frequency electromagnetic fields (Other)
结局指标
主要结局
Sleep Efficiency index
时间窗: 8 hours
(total Sleep time in % of time in bed)
次要结局
- Sleep EEG power(8 hours)
- declarative memory(8 hours)
研究者
Heidi Danker-Hopfe
Head of Competence Center for Sleep Medicine
Charite University, Berlin, Germany