The impact of sleep and waking on memory consolidation in adolescents
- Conditions
- healthy volunteers
- Registration Number
- DRKS00000535
- Lead Sponsor
- niversitätsklinikum Freiburg, Abteilung für Psychiatrie und Psychotherapie
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- Female
- Target Recruitment
- 76
Age: 16 years
Gender: female
Pubertal status late-pubertal (Self-rating scale for pubertal development according to Carskadon: Score = 7)
Right-dominant hand
Students at Gymnasium
Normal and stable sleep behaviour
Normal or corrected-to-normal vision
Girls: have to be in the follicular phase of the menstrual cycle (days 5-15) on test day. Girls on oral contraceptives will be studied within the first three weeks of their pill cycle (menstruation calendar).
Not able to provide informed consent and unsufficient knowledge of German language (Grade for German below 4)
Current or past mental illness (lifetime)
Mental illnesses in first degree relatives
Epilepsy or other chronic diseases
Regular intake of centrally acting medication
Current or past legal and illegal drug abuse or dependence
No regular use of alcohol
Excessive use of caffeine (>300 mg or 3 cups of coffee/day)
Pregnancy (Urinetest)
Claustrphobia
Smoker
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Percent improvement in mirror tracing draw time, Percent recall in the word pair associate task, reduction in ms of the Stimulus Onset Asynchrony (SOA) in the texture discrimination task (TDT) from the test to retest condition.
- Secondary Outcome Measures
Name Time Method Secondary analyses include the correlations between EEG sleep variables (amount of slow wave sleep (SWS) and REM sleep, number of sleep spindles) and memory performance, and cortisol levels.