Evaluation of Quadriceps muscle strength in patients post Covid -19
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 36
- 试验地点
- 1
- 主要终点
- Peak torque (nm)
研究概览
简要总结
COVID 19 is an infectious disease caused by novel corona virus.
Most people infected with COVID 19 virus will experience symptoms from mild to severe that can permanently detract from their quality of life.
There are various systemic factors such as inflammation, hypoxia, malnutrition and local muscle factors such as deconditioning causing extra pulmonary complications in patients with COVID 19.
If a bad case of COVID 19 or any illness keeps you in bed at home or at hospital for days or weeks, your muscle will also lose strength fast. Lying sick in bed for extended period can lead to muscle atrophy- weakening due to limited use.
Healthy people can lose approximately 1% to 1.5% of muscle strength per day with bed rest. Those who are sick may lose even more.
Identifying those patients who have reduced strength between 6 to 12 weeks from the day of testing positive, will allow early intervention targeted at improving quality of life and help them return to their work. Therefore, the aim of the study is to evaluate Quadriceps muscle strength in patients recovered from COVID 19 illness.
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 20.00 Year(s) 至 50.00 Year(s)（—）
- 性别
- All
入选标准
- •Patients recovered from COVID -19 illness 1 Age- 20-50yrs 2 Patients whose RT-PCR test results were positive 3 Post COVID-19 illness.
- •Between 6-12weeks 4 Condition of the patient.
- •Self-ambulatory (without assistive devices) Healthy individuals 1 Age- 20-50yrs.
排除标准
- •Patients recovered from COVID-19 illness 1 Neurologic diseases such as stroke, polyneuropathy, Muscular dystrophy, Myasthenia gravis, Myositis 2 Orthopaedic conditions such as Total knee replacement, Rheumatoid arthritis, Hip and Knee osteoarthritis, osteoporosis and recent fractures(3months) of lower extremity 3 Oncology conditions 4 Cardio-pulmonary conditions such as COPD, congestive heart failure, peripheral artery disease and cardiac arrest Renal conditions such as chronic kidney disease, glomerulonephritis, acute and chronic renal failure 5 Patients who were on steroids as a part of their treatment.
- •Healthy individuals 1 Abuse of alcohol and drugs 2 Involved in rehabilitation or structured exercise programme during previous 3months 3 Neurologic diseases such as stroke, polyneuropathy, Muscular dystrophy, Myasthenia gravis, Myositis 4 Orthopaedic conditions such as Total knee replacement, Rheumatoid arthritis, Hip and Knee osteoarthritis, osteoporosis and recent fractures(3months) of lower extremity 5 Oncology conditions 6 Cardio-pulmonary conditions such as COPD, congestive heart failure, peripheral artery disease and cardiac arrest 7 Renal conditions such as chronic kidney disease, glomerulonephritis, acute and chronic renal failure.
结局指标
主要结局
Peak torque (nm)
时间窗: 6weeks to 12 weeeks
次要结局
- Fatigue index(6 -12 weeks)