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Comparison of local versus systemic tranexamic acid in total knee replacement

Not Applicable
Completed
Conditions
Health Condition 1: null- Primary osteoarthritis knee
Registration Number
CTRI/2017/04/008401
Lead Sponsor
Sri Sathya Sai Institute of Higher Medical Sciences Prasanthigram
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
Not specified
Target Recruitment
138
Inclusion Criteria

1. All patients undergoing total knee arthroplasty for primary arthroplasty knee

2.Patients who are willing to participate in the study.

3.Patient without exclusion criteria.

Exclusion Criteria

1.Allergy to the TXA

2.H/O Coagulopathy,abnormal PT or APTT

3.Past H/O Thromboembolic event

4.Treatment with Aspirin or NSAIDS in the last week

5.plasma creatinine > 115 micro moles /litre for males

And >100 micro moles/litre in females.

6.Acute infection[eg;leukocytosis or fever]

7.Malignancy

8.MI in preceding 12 months,unstable angina

9.Patient who were given plasma in perioperative period.

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Secondary Outcome Measures
NameTimeMethod
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