CTRI/2020/07/026704尚未招募1 期
Analgesic efficacy of adductor canal block (single shot + continuous infusion) versus epidural infusion in patients undergoing unilateral total knee arthroplasty
试验速览
- 阶段
- 1 期
- 状态
- 尚未招募
- 入组人数
- 42
- 试验地点
- 1
- 主要终点
- assess analgesic efficacy by noting the VAS score at rest and on movement postoperatively
研究概览
简要总结
Patients undergoing total knee arthroplasty experience a lot of pain. A good analgesia in turn leads to quicker mobilization and lesser length of hospital stay which in turn is cost effective. In this study, a comparison was made between epidural infusion and adductor canal infusion keeping LIA and systemic analgesics common in both the groups. Another important aspect of this study is the evaluation of pain at 3 months post surgery as the incidence of chronic pain has been seen in approximately 20% of patients postoperatively.
研究设计
- 研究类型
- Interventional
- 分配方式
- Computer generated randomization
- 盲法
- Outcome Assessor Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 80.00 Year(s)（—）
- 性别
- All
入选标准
- •Belonging to ASA 1 and 2 undergoing unilateral arthropathy.
排除标准
- •a)Patients refusiong to give their consent for the study b)Patients refusing Regional Anaesthesia/ or to have any continuous catheters in their body c)Patients having absolute or relative contra- indications to Regional Anaesthesia d)Patients having a revision TKR e)History of neurological abnormality in the operating leg eg.
- •History of chronic pain, stroke or previous nerve injury f)Allergy or any contra- indication to drugs used in this study g)Morbidly obese ( BMI > 40 ) h) History of alcohol or drug abuse.
结局指标
主要结局
assess analgesic efficacy by noting the VAS score at rest and on movement postoperatively
时间窗: 0 hrs, 4 hrs, 8 hrs, 12 hrs, 24 hrs, 48 hrs
次要结局
- 1) Ability to do straight leg raising test suggestive of motor or sensory block as a consequence of ACB or EA 2) Time to first successful ambulation 3) Time to first self micturition in ACB group((as EA group patients catheterized) 4) Analgesics used over 48 hours as a part of multimodal analgesic regimen in both groups 5) adverse events observed in either group 6) Length of hospital stay and 7) Chronic pain at 6 months follow up)
研究者
研究点 (1)
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