CTRI/2025/09/094869Not yet recruitingNot Applicable
Comparison of Two Different Doses of Sugammadex for Reversal of Rocuronium Induced Neuromuscular Blockade
Dr Annie Paul1 site in 1 country66 target enrollmentStarted: October 1, 2025Last updated:
Trial Snapshot
- Phase
- Not Applicable
- Status
- Not yet recruiting
- Sponsor
- Enrollment
- 66
- Locations
- 1
- Primary Endpoint
- Time from administration of Sugammadex to achieving TOFR greater than 0.9
Study Overview
Brief Summary
This study compares the efficacy of two doses of Sugammadex, 1mg per kg and 2mg per kg, a drug used to reverse Rocuronium induced neuromuscular blockade in surgical patients. Outcomes include time to full reversal, percentage achieving target within 5min.
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Masking
- None
Eligibility Criteria
- Ages
- 18.00 Year(s) to 65.00 Year(s) (—)
- Sex
- All
Inclusion Criteria
- •ASA physical status 1 or 2 Surgeries under general anaesthesia with controlled ventilation for equal or greater than 40 minutes duration.
Exclusion Criteria
- •Known hypersensitivity to study drugs Neuromuscular disorders Medications altering effects of NMBA.
Outcomes
Primary Outcomes
Time from administration of Sugammadex to achieving TOFR greater than 0.9
Time Frame: 18 months
Secondary Outcomes
No secondary outcomes reported
Investigators
Dr Annie Paul
Vardhman Mahavir Medical College and Safdarjung Hospital
Study Sites (1)
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