Does Stellate Ganglion Block Decrease Stress Response of Intubation?
试验速览
- 阶段
- 2 期
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- heart rate
研究概览
简要总结
In this study investigators will evaluate the effect of stellate ganglion block on stress response of intubation in comparison to traditional antistress measures in adult patients
详细描述
Both groups will have the same general anesthesia procedure, patients in stellate block group will receive lidocaine in the stellate block will in control group patients will receive Na.Cl as placebo. primary outcome will be stress response to subsequent endotracheal intubation measure by changes in heart rate
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Double (Participant, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 60 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Elective surgery
- •General anesthesia with endotracheal intubation
排除标准
- •Pregnancy
- •Hypersensitivity to local anesthetics
- •Coagulopathy
- •Infection at site of injection
- •Patient refusal
研究组 & 干预措施
stellate block
patients in this arm will receive ultrasonographic guided left stellate block with 6 ml of lidocaine 2% after routine induction of general anesthesia and before endotracheal intubation
干预措施: lidocaine 2% (Drug)
control
patients in this arm will receive ultrasonographic guided left stellate block with 6 ml normal saline (Na.Cl 0.9%) (control group) after routine induction of general anesthesia and before endotracheal intubation
干预措施: stellate block (Procedure)
control
patients in this arm will receive ultrasonographic guided left stellate block with 6 ml normal saline (Na.Cl 0.9%) (control group) after routine induction of general anesthesia and before endotracheal intubation
干预措施: Na.Cl 0.9% (placebo) (Drug)
stellate block
patients in this arm will receive ultrasonographic guided left stellate block with 6 ml of lidocaine 2% after routine induction of general anesthesia and before endotracheal intubation
干预措施: stellate block (Procedure)
结局指标
主要结局
heart rate
时间窗: 5 minutes
measured in beat/min.
次要结局
- mean arterial blood pressure(5 minutes)
研究者
abdelraheem elawamy
lecturer
Assiut University