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Clinical Trials/NCT06044207
NCT06044207
Recruiting
Not Applicable

Biomarkers and Risk Factors for Perioperative Neurocognitive Disorders in Elderly Non-neurosurgical Patients

Jinan Central Hospital1 site in 1 country1,000 target enrollmentJune 1, 2023

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Perioperative Neurocognitive Dysfunction
Sponsor
Jinan Central Hospital
Enrollment
1000
Locations
1
Primary Endpoint
Perioperative neurocognitive dysfunction
Status
Recruiting
Last Updated
2 years ago

Overview

Brief Summary

Basic information and biological samples of patients were collected preoperatively and intraoperatively, and patients were divided into case and control groups by cognitive function assessment postoperatively, and risk factors and biomarkers of perioperative cognitive dysfunction were derived by analyzing and statistically processing basic information and biological samples.

Registry
clinicaltrials.gov
Start Date
June 1, 2023
End Date
January 1, 2026
Last Updated
2 years ago
Study Type
Observational
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Age more than or equal to 65 years old
  • ASA classification Ⅰ\~Ⅲ grade

Exclusion Criteria

  • History of previous Craniocerebral surgery or Craniocerebral trauma
  • Inability to successfully complete preoperative psychological function tests
  • Those who are severely deaf, speech impaired and otherwise unable to communicate.

Outcomes

Primary Outcomes

Perioperative neurocognitive dysfunction

Time Frame: 1 year postoperative

Identification of patients who develop perioperative neurocognitive disorders after surgery by postoperative follow-up with cognitive function tests

Study Sites (1)

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