Predicting Myocardial Infarction After Abdominal Surgery: Clinical Scores & Biomarkers

Completed

• Conditions: Myocardial Infarction

• Registration Number: NCT06767943
• Lead Sponsor: Benha University

Brief Summary

All patients undergoing non-cardiac surgery who met the inclusion criteria underwent a preoperative evaluation using specific assessment tools.

Following surgery, patients were closely monitored in the intermediate care unit for the first 24 hours for the development of acute myocardial infarction (AMI). AMI was diagnosed based on the presence of chest pain, elevated cardiac biomarkers, and specific electrocardiogram (ECG) and echocardiogram findings.

Detailed Description

Not available

Study Timeline

• Study Start: 2024-11-15
• Primary Completion: 2025-01-01
• Study First Submitted: 2025-01-06
• Study First Submitted QC: 2025-01-06
• Study Completion: 2025-01-31
• Status Verified: 2025-03
• Study First Posted: 2025-03-25
• Last Update Submitted: 2025-03-26
• Last Update Posted: 2025-04-01

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

• Patients older than 45,
• Patients of ASA-PS grade II-IV,
• Patients who prepared for non-cardiac surgeries of SSS of II-IV,
• Patients free of exclusion criteria,
• Patients signed the written consent for the study precipitation.

Exclusion Criteria

• Patients of ASA-PS grade I or V,
• Patients younger than 60 years,
• Patients planned to undergo surgeries of SSS >IV,
• Patients were severely frail with CFS>6,
• Patients had abnormal preoperative electrocardiography (ECG),
• Patients had a history of previous major cardiac or cerebrovascular events,
• Patient had disturbed cognitive function, coagulopathy, severe anemia with hemoglobin concentration (HBC) < 7 gm/dl.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The proportion of patients reported having at least a 50% incidence of Myocardial Infarction (measured by the Relevant Changes in 12-Leads ECG) in correlation with blood biomarkers.	50 Days	The incidence of Myocardial infarction after major abdominal surgery detected by relevant changes in 12 leads ECG and in correlation to presence of blood biomarkers

Trial Locations

Locations (1)

Benha University; 🇪🇬 Banhā, El Qalyoubia, Egypt