Clinical Scoring and Biomarkers for Prediction of Myocardial Infarction After Non-Cardiac Surgery (MINS) Syndrome in Patients Undergoing Major Abdominal Surgeries
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 30
- 试验地点
- 1
- 主要终点
- The proportion of patients reported having at least a 50% incidence of Myocardial Infarction (measured by the Relevant Changes in 12-Leads ECG) in correlation with blood biomarkers.
研究概览
简要总结
All patients undergoing non-cardiac surgery who met the inclusion criteria underwent a preoperative evaluation using specific assessment tools.
Following surgery, patients were closely monitored in the intermediate care unit for the first 24 hours for the development of acute myocardial infarction (AMI). AMI was diagnosed based on the presence of chest pain, elevated cardiac biomarkers, and specific electrocardiogram (ECG) and echocardiogram findings.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 年龄范围
- 45 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients older than 45,
- •Patients of ASA-PS grade II-IV,
- •Patients who prepared for non-cardiac surgeries of SSS of II-IV,
- •Patients free of exclusion criteria,
- •Patients signed the written consent for the study precipitation.
排除标准
- •Patients of ASA-PS grade I or V,
- •Patients younger than 60 years,
- •Patients planned to undergo surgeries of SSS >IV,
- •Patients were severely frail with CFS>6,
- •Patients had abnormal preoperative electrocardiography (ECG),
- •Patients had a history of previous major cardiac or cerebrovascular events,
- •Patient had disturbed cognitive function, coagulopathy, severe anemia with hemoglobin concentration (HBC) < 7 gm/dl.
结局指标
主要结局
The proportion of patients reported having at least a 50% incidence of Myocardial Infarction (measured by the Relevant Changes in 12-Leads ECG) in correlation with blood biomarkers.
时间窗: 50 Days
The incidence of Myocardial infarction after major abdominal surgery detected by relevant changes in 12 leads ECG and in correlation to presence of blood biomarkers
次要结局
未报告次要终点
研究者
Mohammed Abd ElRahman Hammed
Assistant Lecturer of Anesthesia, Pain & ICU
Benha University