Daily vs. weekly showering in atopic dermatitis: a randomized controlled clinical trial.<br>

Completed

Conditions: atopic dermatitis
atopic eczema
10014982

Registration Number: NL-OMON42004

Lead Sponsor: Academisch Medisch Centrum

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Completed

Sex: Not specified

Target Recruitment: 46

Inclusion Criteria

Male or female patients with atopic dermatitis (AD) according to the UK working party criteria
Age 4-12 years
Mild to moderate AD (objective SCORAD < 40)
Having access to a shower
Presence of 1 AD lesion and a part of non-lesional skin on preferably the ventral (fore) arm

Exclusion Criteria

Active skin infection requiring antibiotic treatment
Systemic immunomodulatory treatment (for AD or other diseases)
Intolerance to Vaseline paraffin ANA
Unwillingness to use Vaseline paraffin ANA as sole emollient
Usage of tar ointments
Usage of thin bleach baths
Performance of water sports (swimming etc) more than once a week

Study & Design

Study Type: Interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Comparison of change in objective SCORAD from week 4 compared to week 0 between<br /><br>procedure groups.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Comparison of change in Eczema Area and Severity Index (EASI), quality of life,<br /><br>AD symptoms, transepidermal water loss, skin capacitance, natural moisturizing<br /><br>factors and skin lipids in tape strips at week 4 compared to week 0 between<br /><br>procedure groups.<br /><br><br /><br>Used amounts of topical medication and Vaseline paraffin ANA and patient*s<br /><br>preference for once weekly vs daily showering at week 4 will be compared<br /><br>between procedure groups.<br /><br><br /><br>The change in objective SCORAD from week 4 compared to week 0 will be compared<br /><br>between procedure groups, stratified by mild vs moderate AD, and stratified by<br /><br>light skin types (1, 2, 3) vs dark skin types (4, 5, 6).</p><br>